Two new tetralones, pyrolones A (1) and B (2), and a new flavonol glycoside, 2''-O-(4-hydroxybenzoyl)hyperin (3), were isolated from Pyrola calliantha (whole plant), together with six structurally related compounds, including 2''-O-galloylhyperin (4), hyperin (5), formononetin (6), quercetin 3-O-alpha-L-arabinopyranoside (7), quercetin 3-O-alpha-L-arabinofuranoside (8), and kaempferol 3-O-beta-D-galactopyranoside (9). The structures and absolute configurations of the new compounds were elucidated on the basis of spectroscopic (UV, ORD, CD, NMR) and mass-spectrometric (HR-ESI-MS) analyses.
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http://dx.doi.org/10.1002/cbdv.200790242 | DOI Listing |
Asian J Surg
July 2024
Department of Rheumatology, The No.1 Affiliated Hospital of Yunnan University of Chinese Medicine, Kunming, Yunnan, 650021, PR China. Electronic address:
Int J Syst Evol Microbiol
December 2023
State Key Laboratory of Efficient Utilization of Arid and Semi-Arid Arable Land in Northern China, Institute of Agricultural Resources and Regional Planning, Chinese Academy of Agricultural Sciences, Beijing 100081, PR China.
A novel Gram-stain-negative, aerobic, non-motile, rod-shaped bacterium, designated pc2-12, was isolated from the rhizosphere soil of the herb collected from arid areas of Tibet. The strain grew most vigorously with 1 % (w/v) NaCl, at pH 7.0 and at 25 °C.
View Article and Find Full Text PDFMicroorganisms
August 2023
CAAS-CIAT Joint Laboratory in Advanced Technologies for Sustainable Agriculture, Institute of Agricultural Resources and Regional Planning, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
A non-motile, Gram-staining-negative, orange-pigmented bacterium called pc1-10 was discovered in Tibet in the soil around ' roots. The isolate thrived in the temperature range of 10-30 °C (optimal, 25 °C), pH range of 5.0-9.
View Article and Find Full Text PDFJ Ethnopharmacol
November 2022
College of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China. Electronic address:
Ethnopharmacological Relevance: Pyrolae herba is the dried whole plant of Pyrola calliantha H. Andres or Pyrola decorata H. Andres (Pyrolaceae).
View Article and Find Full Text PDFFood Chem Toxicol
April 2017
Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin 150040, PR China. Electronic address:
2'-O-galloylhyperin (2'-O-GH), an active compound isolated from Pyrola calliantha, possesses remarkable antioxidant activity. The aims of this study were to investigate the hepatoprotective effect of 2'-O-GH against oxidative stress and elucidate the underlying mechanistic signaling pathways in HepG2 cells as well as in an animal model. Results showed that 2'-O-GH significantly inhibited hydrogen peroxide (HO)-induced HepG2 cell death in a dose dependent manner.
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