Severity: Warning
Message: fopen(/var/lib/php/sessions/ci_sessionmi7onvttal6jehjnsu58be9nddpogu11): Failed to open stream: No space left on device
Filename: drivers/Session_files_driver.php
Line Number: 177
Backtrace:
File: /var/www/html/index.php
Line: 316
Function: require_once
Severity: Warning
Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)
Filename: Session/Session.php
Line Number: 137
Backtrace:
File: /var/www/html/index.php
Line: 316
Function: require_once
Severity: Warning
Message: file_get_contents(https://...@gmail.com&api_key=61f08fa0b96a73de8c900d749fcb997acc09&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 197
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 197
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 271
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3145
Function: getPubMedXML
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
Different examples of invasion in normal ontogenesis and during the growth of malignant genetically altered cells are discussed. The invasive migration of single epithelial cells or cell groups may be regarded as pathological variants depending on complete or partial epithelio-mesenchymal transformation. A very special new type of epithelial cell dissemination from the monolayer was observed in our experiments with epithelial cells hyperexpressing transfected RhoA gene. In these experiments, mitotic cells were squeezed out of the contracted monolayer into a fluid medium, floated passively in this medium, and settled at the substrate forming new islands. It is important to find whether this type of dissemination not associated with active cell movements can take place in tumors in vivo.
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