We investigated the effect of aging on preoperative oxidative stress by measuring serum hydroperoxide values in 35 patients who underwent elective surgery under general anesthesia. A small amount of blood was withdrawn through an intravenous catheter and serum hydroperoxide values were measured using the Free Radical Analytic System (FRAS4). Aging and oxidative stress are significantly and positively correlated (P < 0.001, r = 0.622). Although the reason is unknown, oxidative stress increases concomitantly with aging.

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