Background: Purpura-free elimination of telangiectases with a single pass of a pulsed dye laser with a large spot has proved difficult.
Objective: The purpose of this report was to define parameters that achieve single-pass purpura-free telangiectasia reduction.
Materials: Thirty patients between the ages of 23 and 78 years were treated with a pulsed dye laser with a 10-mm spot and fluences ranging from 9 to 10 J/cm2. The macropulse width was 20 ms. Each macropulse was composed of eight pulselets. Treatments were carried out over facial areas with discrete telangiectases.
Results: Smaller telangiectases (<600 microm) showed transient bluing followed by stenosis. Larger vessels (600-10,000 microm) showed bluing but inconsistent closure. A second pass typically resulted in closure.
Conclusion: A modified pulsed dye laser was capable of single-pass purpura-free reduction with a 10-mm spot size.
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http://dx.doi.org/10.1111/j.1524-4725.2007.33317.x | DOI Listing |
Photobiomodul Photomed Laser Surg
January 2025
Department of Preventive Dental Sciences, College of Dentistry, Dar Al Uloom University, Riyadh, Saudi Arabia.
Impact of surface conditioner phytic acid (IP6) Er,Cr:YSGG laser (ECYL) methylene blue photodynamic therapy (MB-PDT) on the microleakage and shear bond strength (SBS) of resin-modified glass ionomer cement (RMGIC) to primary sound dentin. Overall, 80 extracted sound primary molars were collected followed by their submergence in self-cure acrylic resin. The dentin surface was exposed and made flat and was assigned into four groups based on the surface conditioning.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
January 2025
Laser Laboratory, Dept. of Physics, The University of Burdwan, Burdwan 713104, India.
The angular dependence of random laser (RL) generation in a commercially available rhodamine 6G (Rh6G) dye has been demonstrated using ZnO-CuO heterostructure as passive scatterers. The grass-like superstructure formed at a 1M:1M molar ratio of ZnO-CuO significantly enhances scattering, resulting in RL spikes with a full width at half maximum (FWHM) of just a few nanometer and a noticeable reduction in the RL threshold. RL emission spectra were collected over an angular spread of 0-180 degrees, revealing a remarkable shift in RL emission from 566 nm to 580 nm.
View Article and Find Full Text PDFMol Pharm
January 2025
Department of Pharmaceutical Sciences, College of Pharmacy, Mercer University, Atlanta, Georgia 30341, United States.
This investigation aimed to enhance transdermal methotrexate delivery through human skin by employing Dr. Pen microneedles and poly(d,l-lactide--glycolide) acid microparticles formulated from eight polymer grades (Expansorb DLG 95-4A, DLG 75-5A, DLG 50-2A, DLG 50-5A, DLG 50-8A, DLG 50-6P, DLG 50-7P, and DLL 10-15A). A comprehensive characterization of the microparticles was performed, encompassing various parameters such as size, charge, morphology, microencapsulation efficiency, yield, release kinetics, and chemical composition.
View Article and Find Full Text PDFOrphanet J Rare Dis
January 2025
Child Neuropsychiatry Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
Background: Sturge-Weber Syndrome (SWS) is a rare, sporadic neurocutaneous disorder affecting the skin, brain, and eyes, due to somatic activating mutations in GNAQ or, less commonly, GNA11 gene. It is characterized by at least two of the following features: a facial capillary malformation, leptomeningeal vascular malformation, and ocular involvement. The spectrum of clinical manifestations includes headache, seizures, stroke-like events, intellectual disability, glaucoma, facial asymmetry, gingival hyperplasia, etc.
View Article and Find Full Text PDFPhotodiagnosis Photodyn Ther
January 2025
Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran. Electronic address:
Background: Candida albicans is the primary cause of vulvovaginal candidiasis, a worldwide health concern for women. The use of supplemental methods, such as antimicrobial photodynamic therapy (aPDT) and probiotics, was promoted by the ineffectiveness of the existing antifungal drugs.
Methods: This study examines the combined effects of probiotics (Bacillus and Enterococcus isolated from the fermented pickles) and PDT (using red laser (655 nm, 18 J/cm) as a light source and methylene blue dye (30 mg/mL) as a photosensitizer) on the in vitro virulence activity of C.
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