Following a bout of high-intensity exercise of short duration (preload stimulus), the muscle is in both a fatigued and a potentiated (referred to as postactivation potentiation) state. Consequently, subsequent muscle performance depends on the balance between these 2 factors. To date, there is no uniform agreement about the optimal recovery required between the preload stimulus and subsequent muscle performance to gain optimal performance benefits. The aim of the present study was to determine the optimal recovery time required to observe enhanced muscle performance following the preload stimulus. Twenty-three professional rugby players (13 senior international players) performed 7 countermovement jumps (CMJs) and 7 ballistic bench throws at the following time points after a preload stimulus (3 repetition maximum [3RM]): baseline, approximately 15 seconds, and 4, 8, 12, 16, and 20 minutes. Their peak power output (PPO) was determined at each time point. Statistical analyses revealed a significant decrease in PPO for both the upper (856 +/- 121 W vs. 816 +/- 121 W, p < 0.001) and the lower (4,568 +/- 509 W vs. 4,430 +/- 495 W, p = 0.005) body when the explosive activity was performed approximately 15 seconds after the preload stimulus. However, when 12 minutes was allowed between the preload stimulus and the CMJ and ballistic bench throws, PPO was increased by 8.0 +/- 8.0% and 5.3 +/- 4.5%, respectively. Based on the above results, we conclude that muscle performance (e.g., power) can be significantly enhanced following a bout of heavy exercise (preload stimulus) in both the upper and the lower body, provided that adequate recovery (8-12 minutes) is given between the preload stimulus and the explosive activity.
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http://dx.doi.org/10.1519/R-20996.1 | DOI Listing |
Biol Sport
October 2024
School of Human Sciences (Exercise and Sport Science), University of Western Australia, Perth, Western Australia.
We evaluated the effects of post-activation performance enhancement through flywheel exercise with varying inertial loads compared to traditional resistance exercise on countermovement jump performance and muscle recruitment. In a randomized crossover design, 13 trained men completed four main experimental trials after three familiarization sessions. These conditions included a traditional trial consisting of 5 sets of 1 repetition using the Smith machine (SM) squat at 90% 1RM, and three flywheel ergometer trials.
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October 2023
Division of Cardiology, Department of Internal Medicine, Yale University, New Haven, CT, United States.
We seek to elucidate the precise nature of mechanical loading that precipitates conduction deficits in a concealed-phase model of arrhythmogenic cardiomyopathy (ACM). ACM is a progressive disorder often resulting from mutations in desmosomal proteins. Exercise has been shown to worsen disease progression and unmask arrhythmia vulnerability, yet the underlying pathomechanisms may depend on the type and intensity of exercise.
View Article and Find Full Text PDFAnal Chem
May 2022
CAS Key Laboratory of Chemistry of Northwestern Plant Resources, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Lanzhou 730000, People's Republic of China.
Stimulus-responsive fluorescent probes have broad applications in the early detection and treatment of tumors and thus promote the personalized treatment of tumors and improve patient survival. Among the repertoires of probes, dual-locked near-infrared (NIR) fluorescent probes are of great significance due to their improved specificity and multiplex detection in tumor imaging but remain to be explored. In this work, a facile noncovalent strategy for constructing dual-locked probes was proposed.
View Article and Find Full Text PDFPLoS One
April 2022
Sports Science Department, Aspire Academy, Doha, Qatar.
The purpose of this research was to establish the optimal recovery duration following a pre-load stimulus on performance measures related to handball players. Seventeen senior male University handball players (mean ± SD: age 23.6 ± 2.
View Article and Find Full Text PDFJ R Soc Interface
February 2022
Center for Advanced Biomaterials for Healthcare@CRIB, Istituto Italiano di Tecnologia (IIT), Largo Barsanti e Matteucci 53, 80125 Naples, Italy.
In cancer therapy, stimulus-responsive drug delivery systems are of particular interest for reducing side effects in healthy tissues and improving drug selectivity in the tumoral ones. Here, a strategy for the preparation of a photo-responsive cross-linked trilayer deposited onto an oil-in-water nanoemulsion via a layer-by-layer technique is reported. The system is made of completely biocompatible materials such as soybean oil, egg lecithin and glycol chitosan, with heparin as the polymeric shell.
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