Objective: To establish the characteristic fingerpint from Phlomis younghustbandii.
Methods: The different collecting time and county samples of Phlomis younghusbandii were determined by HPLC.
Results: The HPLC-FPC of Phlomis younghusbandii was set up by establishing 14 common peaks. Accuracy, stability and repeatability of the method were good.
Conclusion: The peaks in the spectrum were all separated perfectly, which met the regulation of HPLC-FPC.
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Dose Response
September 2024
Nursing Department, Affiliated Hospital of Xizang Minzu University, Xianyang, China.
Mol Immunol
April 2019
Department of Pharmacy, Shaanxi Provincial Hospital of Tuberculosis Prevention and Treatment, Xi'an 710100, PR China. Electronic address:
High altitude cerebral edema (HACE), whose development process is associated with oxidative stress and inflammatory response, is a life-threatening condition caused by rapid ascent speed to high altitudes. Phenylethanoid glycosides (PhGCs) are primary active constituents isolated from Phlomis younghusbandii Mukerjee that reportedly exhibit potent anti-oxidant and anti-inflammatory activities. The present study aims to investigate the protective effect of phenylethanoid glycosides (PhGCs) from P.
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December 2017
Department of Emergency Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830054, P.R. China.
Imperatorin (IMT) is a furanocoumarin from the root of Phlomis younghusbandii (Lamiaceae) with various activities. In the present study, the anti‑inflammatory effects of IMT were evaluated by examining dimethylbenzene‑induced ear edema, acetic acid‑induced vascular permeability and by performing cotton pellet granuloma assessments in mice. In addition, the expression of pro‑inflammatory cytokines, including tumor necrosis factor (TNF)‑α, interleukin (IL)‑6 and IL‑1β, were detected using enzyme‑linked immunosorbent assay kits in mice and using reverse transcription polymerase chain reaction analysis in RAW 264.
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February 2017
Rheumatism Immunity Branch, Taian Central Hospital, Taian, Shandong 271000, P.R. China.
Mukerjee (Labiatae) has been reported to be effective in the treatment of rheumatoid arthritis (RA). In the present study, the anti-inflammatory and anti-arthritic effects of phlomisoside F (PF), isolated from Mukerjee (Labiatae), were investigated in male Wistar rats subjected to carrageen-induced paw edema and complete Freund's adjuvant (CFA)-induced arthritis. Arthritis scores were evaluated by a 5-point ordinal scale (scores 0-4).
View Article and Find Full Text PDFInt Immunopharmacol
September 2015
Department of Anesthesia, the Third Hospital of Jinan, Jinan 250132, PR China.
This study was designed to investigate the anti-inflammatory effect of phlomisoside F (PMF) isolated from Phlomis younghusbandii and to explore the possible pharmacological mechanisms. Anti-inflammatory effects of PMF were evaluated by using carrageenan-induced rat paw edema test, dimethylbenzen-induced ear edema test, acetic acid-induced vascular permeability and cotton pellet granuloma test. Furthermore, the releases of pro-inflammatory cytokines (TNF-α, IL-6 and IL-1β) were determined by ELISA.
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