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Doxycycline Trap: A Case Report on the Unexpected Development of an Oesophageal Ulcer.
Cureus
October 2024
Gastroenterology, Clinic for gastroenterology and hepatology, Kragujevac, SRB.
The phenomenon of drug-induced mucosal damage has not been reported much in the literature, although over 100 drugs are known to cause this condition. Tetracyclines contribute the most to mucosal damage. The common symptoms are difficulty swallowing, pain while swallowing, and possibly retrosternal pain.
View Article and Find Full Text PDFEsophageal lymphocytosis: exploring the knowns and unknowns of this pattern of esophageal injury.
Expert Rev Gastroenterol Hepatol
September 2024
Diagnostic and Research Institute of Pathology, Diagnostic and Research Center for Molecular BioMedicine, Medical University of Graz, Graz, Austria.
Article Synopsis
- Lymphocyte-rich inflammation of the esophagus is an emerging condition characterized by symptoms like difficulty swallowing and food blockages, often appearing similar to eosinophilic esophagitis during endoscopy.
- Three main subtypes of this inflammation have been identified: lymphocytic, lichenoid, and lymphocyte-predominant esophagitis, which must be differentiated from other causes such as gastro-esophageal reflux and Candida infections.
- The review highlights the need for systematic diagnostic criteria and recommends more research to understand the disease's progression and improve treatment strategies for affected patients.
Esophageal and Ileal Ulcers Caused by Hydroxycarbamide: A Case Report and Literature Review.
Intern Med
August 2024
Division of General Internal Medicine, Jichi Medical University Hospital, Japan.
Article Synopsis
- Hydroxycarbamide is an antimetabolic drug used to manage myeloproliferative disorders but can lead to side effects such as myelosuppression, skin ulcers, and oral mucositis.
- A 74-year-old woman developed both esophageal and ileal ulcers following hydroxycarbamide treatment, a rare occurrence not previously documented for this medication.
- The case suggests that hydroxycarbamide may cause gastrointestinal ulcers, and stopping the medication often leads to quick recovery; thus, new symptoms should prompt consideration of drug-related causes for diagnosis and treatment.
Teratogenic effects of voriconazole (anti-fungal drug) on Swiss albino mice.
Reprod Toxicol
October 2024
Department of life science and environmental science, Research scholar, Professor and Associate Professor, IIS (deemed to be University), Jaipur, Rajasthan 302020, India. Electronic address:
Antifungals are a class of drugs that target the treatment of invasive fungal infections. This includes polyenes, triazoles, and echinocadins. Among these, azoles are being extensively used nowadays.
View Article and Find Full Text PDFGastroenterology healthcare in LGBTQ+ individuals.
Eur J Gastroenterol Hepatol
September 2024
Gastroenterology Department, Centro Hospitalar Universitário de São João.
Lesbian, gay, bisexual, transgender, queer, or questioning individuals, as well as those with another diverse identity (LGBTQ+), present specific nuances in healthcare that physicians must consider in clinical practice. Particularly, gastroenterologists are nowadays facing different issues in several fields regarding LGBTQ+ healthcare, such as endoscopy, inflammatory bowel disease, hepatology, and proctology. In this study, the authors provide a practice-oriented and up-to-date review reinforcing the importance of some of the most prevalent pathologies associated with sexuality that gastroenterologists may encounter in their clinical practice.
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