Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/15459620701798224 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A fully human IgG1 antibody targeting connexin 32 extracellular domain blocks CMTX1 hemichannel dysfunction in an in vitro model.
Cell Commun Signal
December 2024
CNR Institute of Biochemistry and Cell Biology, Monterotondo, Rome, 00015, Italy.
Connexins (Cxs) are fundamental in cell-cell communication, functioning as gap junction channels (GJCs) that facilitate solute exchange between adjacent cells and as hemichannels (HCs) that mediate solute exchange between the cytoplasm and the extracellular environment. Mutations in the GJB1 gene, which encodes Cx32, lead to X-linked Charcot-Marie-Tooth type 1 (CMTX1), a rare hereditary demyelinating disorder of the peripheral nervous system (PNS) without an effective cure or treatment. In Schwann cells, Cx32 HCs are thought to play a role in myelination by enhancing intracellular and intercellular Ca signaling, which is crucial for proper PNS myelination.
View Article and Find Full Text PDFAffordable paper-based strips: A breakthrough in phenol detection for water samples.
Spectrochim Acta A Mol Biomol Spectrosc
March 2025
Graduate School of Integrated Energy-AI, Jeonbuk National University, Jeonju 54896, the Republic of Korea. Electronic address:
Article Synopsis
- Phenols are common industrial pollutants found in sectors like pharmaceuticals and agriculture, often released untreated, necessitating effective detection methods.
- Current detection techniques like spectrophotometry and chromatography are costly and complex, highlighting the need for a simpler, affordable solution.
- This study presents a new method using low-cost colorimetric paper-based sensor strips to detect phenols in water using the Folin-Ciocalteu reagent, achieving high recovery rates with promising detection limits.
Comparison of Survivin Determination by Surface-Enhanced Fluorescence and Raman Spectroscopy on Nanostructured Silver Substrates.
Biosensors (Basel)
October 2024
Immunoassays/Immunosensors Laboratory Institute of Nuclear & Radiological Sciences & Technology, Energy & Safety, NCSR "Demokritos", 15341 Aghia Paraskevi, Greece.
Survivin belongs to a family of proteins that promote cellular proliferation and inhibit cellular apoptosis. Its overexpression in various cancer types has led to its recognition as an important marker for cancer diagnosis and treatment. In this work, we compare two approaches for the immunochemical detection of survivin through surface-enhanced fluorescence or Raman spectroscopy using surfaces with nanowires decorated with silver nanoparticles in the form of dendrites or aggregates as immunoassays substrates.
View Article and Find Full Text PDFQuantum Dot-Based Nanosensors for In Vitro Detection of .
Nanomaterials (Basel)
September 2024
Laboratory of Laser Molecular Imaging and Machine Learning, National Research Tomsk State University, 634050 Tomsk, Russia.
Article Synopsis
- * Various diagnostic methods exist to detect TB biomarkers like DNA, proteins, and antibodies using techniques such as PCR, ELISA, and flow cytometry, which help identify infections through optical signals.
- * Recent advancements in biosensing focus on enhancing detection sensitivity using fluorescent quantum dots, which offer brighter and more stable optical tags for identifying TB biomarkers more effectively.
A 3D-Printed Do-It-Yourself ELISA Plate Reader as a Biosensor Tested on TNFα Assay.
Biosensors (Basel)
July 2024
Military Faculty of Medicine, University of Defence, Trebesska 1575, CZ-50001 Hradec Kralove, Czech Republic.
Simple analytical devices suitable for the analysis of various biochemical and immunechemical markers are highly desirable and can provide laboratory diagnoses outside standard hospitals. This study focuses on constructing an easily reproducible do-it-yourself ELISA plate reader biosensor device, assembled from generally available and inexpensive parts. The colorimetric biosensor was based on standard 96-well microplates, 3D-printed parts, and a smartphone camera as a detector was utilized here as a tool to replace the ELISA method, and its function was illustrated in the assay of TNFα as a model immunochemical marker.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!