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Background: Atrial fibrillation (AF) has a significant impact on health and quality of life. The relationship of AF burden and temporal patterns of AF on patient symptoms, outcomes, and healthcare utilization is unknown. Insertable cardiac monitors (ICMs) are a strategic and as yet untapped, tool to investigate these relationships.
View Article and Find Full Text PDFLncRNA NORAD sponging to miR-26b-5p represses the progression of Alzheimer's disease in vitro by upregulating MME expression.
Cytotechnology
February 2025
Department of Neurology, Hubei Provincial Hospital of Integrated Traditional and Western Medicine, Jianghan District, No. 11 Lingjiaohu Road, Wuhan, 430015 China.
Unlabelled: Alzheimer's disease (AD) is a progressive neurological condition that causes brain shrinkage and cell death. This study aimed to identify the role of the NORAD/miR-26b-5p axis in AD. StarBase was used to examine the binding sequences of miR-26b-5p to LncRNA NORAD or its target genes, which were verified by a double luciferase reporter assay.
View Article and Find Full Text PDFAnalysis of choroidal thickness, macular thickness, peripapillary retinal nerve fiber layer thickness, and macular vascular density in children with unilateral amblyopia using swept-source optical coherence tomography and their changes following occlusion therapy.
Taiwan J Ophthalmol
June 2024
Department of Vitreo-Retina, Sankara Eye Hospital, Shimoga, Karnataka, India.
Purpose: The purpose of this study was to analyze choroidal thickness (CT), along with macular thickness (MT), peripapillary retinal nerve fiber layer thickness (RNFLT), and macular vascular density (MVD) using swept-source optical coherence tomography (SS-OCT) in children with unilateral amblyopia, and compare the same with normal fellow eyes and normal eyes of normal children before and following occlusion therapy.
Materials And Methods: This was a prospective, longitudinal study of 60 children (4-18 years); 30 children had unilateral amblyopia and remaining 30 were normal. Group 1 consisted of 30 amblyopic eyes of children with unilateral amblyopia; Group 2 consisted of 30 fellow normal eyes of Group 1; Group 3 consisted of normal eyes of normal children.
Identification of Candidate Characteristics that Predicted a Successful Anesthesiology Residency Program Match in 2024: An Anonymous, Prospective Survey.
J Educ Perioper Med
January 2025
Tricia Pendergrast is a Resident Physician in the Department of Anesthesiology at University of Michigan, Ann Arbor, MI. Jed Wolpaw is the Core Residency Program Director in the Department of Anesthesiology and Critical Care Medicine at Johns Hopkins University School of Medicine, Baltimore, MD. Michael P. Hofkamp is the Director of Undergraduate Medical Education in the Department of Anesthesiology at Baylor Scott & White Medical Center-Temple, Temple, TX.
Background: The primary aim of our study was to identify candidate characteristics that predicted a successful outcome for applicants to anesthesiology residency programs in the 2024 Main Residency Match. The secondary aim of our study was to assess the impact of gold and silver signals on the application process.
Methods: The Baylor Scott & White Research Institute institutional review board approved this study.
Comparison of Outcomes of Hinge Craniotomy Versus Decompressive Craniectomy in Patients With Malignant Intracranial Hypertension: A Prospective, Randomized Controlled Study.
Korean J Neurotrauma
December 2024
Department of Neurosurgery, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Objective: This randomized controlled trial (RCT) aimed to compare the short-, mid-, and long-term outcomes in patients with malignant intracranial hypertension undergoing either decompressive craniectomy (DC) or hinge craniotomy (HC).
Methods: In this prospective RCT, 38 patients diagnosed with malignant intracranial hypertension due to ischemic infarction, traumatic brain injury, or non-lesional spontaneous intracerebral hemorrhage, who required cranial decompression, were randomly allocated to the DC and HC groups.
Results: The need for reoperation, particularly cranioplasty, in the DC group was significantly different from that in the HC group.
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