AI Article Synopsis

  • The estuarine fish Fundulus heteroclitus serves as a valuable model for studying interactions between individuals and their environment, due to extensive research on their adaptive responses to different conditions.
  • This body of work has significantly enhanced our knowledge in areas like physiology, gene regulation, toxicology, and genetics, not only for Fundulus but also for other vertebrates.
  • The current research is limited by a lack of genomic resources, and creating a more comprehensive genomics toolbox for these species could lead to major advances in understanding biological mechanisms and ecological strategies across vertebrates.

Article Abstract

A strong foundation of basic and applied research documents that the estuarine fish Fundulus heteroclitus and related species are unique laboratory and field models for understanding how individuals and populations interact with their environment. In this paper we summarize an extensive body of work examining the adaptive responses of Fundulus species to environmental conditions, and describe how this research has contributed importantly to our understanding of physiology, gene regulation, toxicology, and ecological and evolutionary genetics of teleosts and other vertebrates. These explorations have reached a critical juncture at which advancement is hindered by the lack of genomic resources for these species. We suggest that a more complete genomics toolbox for F. heteroclitus and related species will permit researchers to exploit the power of this model organism to rapidly advance our understanding of fundamental biological and pathological mechanisms among vertebrates, as well as ecological strategies and evolutionary processes common to all living organisms.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128618PMC
http://dx.doi.org/10.1016/j.cbd.2007.09.001DOI Listing

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