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Late-Onset Dystonia With Low-Dose Olanzapine in an Older Person: A Case Report.
Sr Care Pharm
October 2021
3Director of Inpatient Geriatric Medicine Clinical Services, Brookdale Dept. of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
Drug-induced dystonias are rare but can occur with second-generation antipsychotics. They are usually dose-related and occur soon after dose initiation. This case describes the development of dystonia after two years of olanzapine 5 mg daily in an older person with Alzheimer's dementia.
View Article and Find Full Text PDFOlanzapine-induced Concurrent Tardive Dystonia and Tardive Dyskinesia in Schizophrenia with Intellectual Disability: A Case Report.
Clin Psychopharmacol Neurosci
November 2020
Department of Neuropsychiatry, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, Korea.
Tardive dystonia and tardive dyskinesia (TDs) are rare extrapyramidal side effects that develop after long-term use of antipsychotics, but they are different syndromes and rarely occur at the same time. Olanzapine is an atypical antipsychotic drug associated with a low risk of extrapyramidal side effects in schizophrenia, but its associations with tardive movements are not clear. We present a case of a 19-year-old Asian female patient with schizophrenia and intellectual disabilities who developed concurrent TDs after long-term use of olanzapine.
View Article and Find Full Text PDFClozapine Treatment of Olanzapine-induced Tardive Dyskinesia: A Case Report.
J Psychiatr Pract
January 2017
SANGROULA: Psychiatry Department, Jamaica Hospital Medical Center, Jamaica, NY VIRK: Interfaith Medical Center, Brooklyn, NY MOHAMMAD: Montefiore Medical Center, Bronx, NY KAHN: Columbia University College of Physicians and Surgeons, New York, NY.
Tardive dyskinesias (TD) are serious, often irreversible side effects of dopamine blocking agents, most commonly first-generation antipsychotics. No definitive treatment exists, with different interventions showing inconsistent results. We report a case of TD presenting after 12 years of olanzapine therapy in a 66-year-old Hispanic male with paranoid schizophrenia.
View Article and Find Full Text PDFTardive Blepharospasm and Meige Syndrome during Treatment with Quetiapine and Olanzapine.
Noro Psikiyatr Ars
June 2015
Clinic of Psychiatry, Bakırköy Prof. Dr. Mazhar Osman Psychiatric Training and Research Hospital, İstanbul, Turkey.
Meige syndrome, which has been presented in tardive syndromes, is a form of blepharospasm accompanied by oromandibular dystonia with manifestations over the face, jaw, and neck. A blepharospasm can be induced by antihistamines, dopaminomimetic or sympathomimetic drugs, or long-term exposure to dopamine antagonists. Atypical antipsychotics have less extrapyramidal side effects because of a weak dopamine D2 receptor binding affinity or a strong antagonistic effect to serotonin 5-HT2a receptor and have been known to cause less tardive dyskinesia than typical antipsychotics.
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