Positive family history is one of the risk factors of glaucoma. It indicates that gene defect may play an important role in the development of glaucoma. The advancement of genetic research provides more strategies to understand the genetic mechanism of glaucoma. The precondition of understanding and studying the genetic factors is the possession of enough genetic resource related to diseases. Based on the usage of glaucomatous genetic resources, several genes and loci related to primary glaucoma were determined abroad. Although we hold the richest human genetic resources of diseases in China, there exist some problems in the collection, storage and usage of the genetic resources of diseases, including the lack of the strict guideline in practice, the lack of the active participant from the clinician, not closely work together of the researchers and clinician, in-sufficiently use of the genetic resources, loss of the genetic resources. We should envisage these problems. At present, it is urgent to rationally and use the genetic resource in China.
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