Objectives: To assess the proportion and clinical significance of bacteraemia caused by viridans streptococci (VS) in immunocompetent adults and children.
Methods: Over a 25-month period, we collected data on all patients with VS bacteraemia at a UK district general hospital.
Results: VS caused 50/723 (6.9%) adult and 13/106 (12.3%) paediatric community-acquired bacteraemias. Of the 43 adult and 12 paediatric patient notes reviewed, 26 (47.3%) cultures were of 'definite' or 'probable' clinical significance. No patients were neutropenic and overall penicillin resistance was 11/55 (20.0%). Amongst adults, there were five (11.6%) confirmed or suspected cases of infective endocarditis compared to none in the paediatric cohort. Similar proportions of adults (16.3%) and children (16.7%) had lower respiratory tract infections. Among non-significant cultures, a history of seizures was observed in one (1.3%) adult and four (33.3%) children (p=0.008). Thirty-day mortality was 7.3%. No children and four adults died, one directly attributable to infection. Median adult inpatient stay was 11 days compared to 2 days in the paediatric population (p=0.003).
Conclusion: Despite cases of infective endocarditis and an incidence of penicillin resistance of 20%, mortality directly attributable to VS infection in immunocompetent adults and children was rare.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jinf.2007.10.012 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Are three zebras more than three frogs: examining conceptual and physical congruency in numerosity judgements of familiar objects.
Psychol Res
December 2024
Brain and Cognition, KU Leuven, Leuven, Belgium.
Researchers in numerical cognition have extensively studied the number sense-the innate human ability to extract numerical information from the environment quickly and effortlessly. Much of this research, however, uses abstract stimuli (e.g.
View Article and Find Full Text PDFThe Cognitive Profile in Adolescents With Anorexia Nervosa and the Relationship With Autism and ADHD: A Pilot Study.
Eur Eat Disord Rev
December 2024
Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden.
Objective: We aimed to examine the cognitive profile in adolescents with anorexia nervosa (AN) and its association with traits of autism spectrum disorder (ASD) and ADHD. In addition, resemblance in the cognitive profile between youths with AN and their parents was explored.
Methods: Adolescent females with acute AN (n = 20) and a healthy comparison group (n = 28) completed neuropsychological tasks of set-shifting (Trail making test, Wisconsin Card Sorting Test) and central coherence (Rey Complex Figures Task, Group Embedded Figures Test, object assembly subtest).
Psychosocial correlates of alcohol and substance use in college youth with type 1 diabetes.
J Pediatr Psychol
December 2024
Division of General Internal Medicine and Health Services Research, David Geffen School of Medicine at the University of California, Los Angeles (UCLA), Los Angeles, CA, United States.
Objective: Adolescents and young adults with chronic diseases face unique challenges during the college years and may consume alcohol and other substances to cope with stressors. This study aimed to assess the patterns of substance use and to determine psychosocial correlates of these behaviors among college youth with type 1 diabetes (T1D).
Methods: College youth with T1D were recruited via social media and direct outreach into a web-based study.
Background: To analyse the epidemiological characteristics of orthopaedic trauma patients and thereby optimize healthcare resource allocation and improve treatment efficiency.
Materials And Methods: Relying on the hospital information system (HIS) database, we retrospectively analysed the epidemiological characteristics of orthopaedic trauma inpatients in our hospital between 2013 and 2022, including patient demographic information, causes of injury, location of injury and hospitalization costs.
Results: The median age of the patients was 36 (26-47) years old; the age stratification of the patients was highest in the proportion of patients aged 40-50 years old (29.
Family Genetic Risk Communication and Reverse Cascade Testing in the BabySeq Project.
Genet Med
December 2024
Division of Genetics and Genomics, Boston Children's Hospital, Boston, MA; The Manton Center for Orphan Disease Research, Boston Children's Hospital, Boston, MA; Harvard Medical School, Boston, MA.
Purpose: Genomic sequencing of newborns (NBSeq) can initiate disease surveillance and therapy for children, and may identify at-risk relatives through reverse cascade testing. We explored genetic risk communication and reverse cascade testing among families of newborns who underwent exome sequencing and had a risk for autosomal dominant disease identified.
Methods: We conducted semi-structured interviews with parents of newborns enrolled in the BabySeq Project who had a pathogenic or likely-pathogenic (P/LP) variant associated with an autosomal dominant (AD) childhood- and/or adult-onset disease returned.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!