A rare case of classic testicular seminoma in an 86-year-old shows similar proliferation rate as in younger men.

Urology

Department of Surgery, Division of Urology, University of Western Ontario, London Health Sciences Centre-Victoria Hospital, London, Ontario, Canada.

Published: November 2007

We present a rare case of classic seminoma in an 86-year-old man. Combined mitotic count, the presence or absence of intravascular invasion, and the expression of PCNA, Ki67, and p53 were compared between this octogenarian and the tumors of four randomly selected standard younger men. These histologic features were chosen to compare the potential biologic activity of these tumors. The phenotype of classic seminomas in octogenarians seems to be the same as in younger men, and treatment paradigms should remain unchanged.

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http://dx.doi.org/10.1016/j.urology.2007.08.006DOI Listing

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