Objective: To investigate the prevalence of microalbuminuria in persons with various glucose tolerance levels and the risk factors for the development of microalbuminuria.
Methods: Early morning urine samples were collected from 1,779 subjects with all the data necessary for this survey from a population screened in Baoshan Community, Shanghai by cluster sampling, including 752 with normal glucose tolerance (NGT), 505 impaired glucose tolerance (IGR), and 522 type 2 diabetes mellitus (T2DM) diagnosed according to a 75 g oral glucose tolerance test (OGTT). Urinary albumin-to-creatinine ratio (ACR) was measured by rate-nephelometry method.
Results: (1) The incidence rate of MAU of the T2DM group was 11.3%, significantly higher than those of the NGT and IGR groups (4.7% and 6.1% respectively, both P < 0.01). (2) Logistic regression showed that MAU was significantly correlated with 2 h PG, systolic blood pressure, and triglyceride.
Conclusion: The prevalence of MAU is significantly higher in the diabetic patients. 2 h PG, systolic blood pressure, and triglyceride and independent risk factors of MAU.
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