With the worldwide prevalence of cardiovascular diseases, much attention has been focused on simulating the characteristics of the human heart to better understand and treat cardiac disorders. The purpose of this study is to build a finite element model of the left atrium (LA) that incorporates detailed anatomical features and realistic material characteristics to investigate the interaction of heart tissue and surgical instruments. This model is used to facilitate the design of an endoscopically deployable atrial retractor for use in minimally invasive, robotically assisted mitral valve repair. Magnetic resonance imaging (MRI) scans of a pressurized explanted porcine heart were taken to provide a 3D solid model of the heart geometry, while uniaxial tensile tests of porcine left atrial tissue were conducted to obtain realistic material properties for noncontractile cardiac tissue. A finite element model of the LA was constructed using ANSYS Release 9.0 software and the MRI data. The Mooney-Rivlin hyperelastic material model was chosen to characterize the passive left atrial tissue; material constants were derived from tensile test data. Finite element analysis (FEA) models of a CardioVations Port Access retractor and a prototype endoscopic retractor were constructed to simulate interaction between each instrument and the LA. These contact simulations were used to compare the quality of retraction between the two instruments and to optimize the design of the prototype retractor. Model accuracy was verified by comparing simulated cardiac wall deflections to those measured by MRI. FEA simulations revealed that peak forces of approximately 2.85 N and 2.46 N were required to retract the LA using the Port Access and prototype retractors, respectively. These forces varied nonlinearly with retractor blade displacement. Dilation of the atrial walls and rigid body motion of the chamber were approximately the same for both retractors. Finite element analysis is shown to be an effective tool for analyzing instrument/tissue interactions and for designing surgical instruments. The benefits of this approach to medical device design are significant when compared to the alternatives: constructing prototypes and evaluating them via animal or clinical trials.
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http://dx.doi.org/10.1115/1.2801650 | DOI Listing |
J Phys Chem A
January 2025
Department of Chemistry, Faculty of Science, University of Helsinki, P.O. Box 55, A.I. Virtanens Plats 1, University of Helsinki FI-00014, Finland.
We point out that although a litany of studies have been published on atoms in hard-wall confinement, they have either not been systematic, having only looked at select atoms and/or select electron configurations, or they have not used robust numerical methods. To remedy the situation, we perform in this work a methodical study of atoms in hard-wall confinement with the HelFEM program, which employs the finite element method that trivially implements the hard-wall potential, guarantees variational results, and allows for easily finding the numerically exact solution. Our fully numerical calculations are based on nonrelativistic density functional theory and spherically averaged densities.
View Article and Find Full Text PDFFront Bioeng Biotechnol
January 2025
Department of Biomedical Engineering and Chemical Engineering, University of Texas at San Antonio, San Antonio, TX, United States.
Introduction: Research on head impact characteristics, especially position-specific investigations in football, has predominantly focused on collegiate and professional levels, leaving a gap in understanding the risks faced by high school players. Therefore, this study aimed to investigate the effect of three factors-player position, impact location, and impact type-on the frequency, severity, and characteristics of impacts in high school American football. Additionally, we examined whether and how player position influences the distribution of impact locations and types.
View Article and Find Full Text PDFAdvancements in plasmonic sensing require simultaneous detection capability that ensures large-scale detection with reduced losses. In this work, we propose a new solid-core fiber-based refractive index (RI) sensor with an ultra-broad detection range. The proposed fiber consists of a relatively simple single-ring cladding with six circular tubes in which the light is guided in the core based on the inhibited-coupling (IC) mechanism.
View Article and Find Full Text PDFFilm-coupled plasmonic resonators offer efficient platforms for light enhancement due to the excitation of gap surface plasmons (GSPs) at metal-insulator-metal interfaces, where electromagnetic energy is stored within the spacer. In applications like biosensing and spontaneous emission control, spatial overlap between the target molecule and plasmonic hotspots is essential. Here, we propose utilizing the controllable, efficient light enhancement capabilities of a specifically designed GSP disk resonator for biosensing and spontaneous emission enhancement.
View Article and Find Full Text PDFPrecision glass molding (PGM) technology, as an efficient and straightforward method for producing glass lenses, has been widely applied in the mass production of aspheric glass lenses. However, molding complex surfaces such as free-form and array surfaces is still in its infancy. To reveal the variations of temperature and stress of microlens array (MLA) optical elements during the molding process, a simulation model was established using the finite element method (FEM), and the heating and forming stages of a chalcogenide glass MLA optical element were studied.
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