Stereoselective functionalization of the 1'-position of 4'-thionucleosides was achieved using a stereoselective S(N)2 reaction controlled by 5-membered ring coordination.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8611653PMC
http://dx.doi.org/10.1080/15257770701508588DOI Listing

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