Objective: To evaluate the spermatotoxicity of gold nanoparticles.
Design: Experimental study.
Setting: A university in Thailand.
Patient(s): Single-donor fresh semen sample.
Intervention(s): A mixture of gold nanoparticle solution and semen was prepared and further analyzed.
Main Outcome Measure(s): Spermatozoa appearance.
Result(s): After mixing the semen with a gold nanoparticle solution, 25% of sperm were not motile. Penetration of gold nanoparticle into the sperm heads and tails was observed.
Conclusion(s): Spermatotoxicity of the gold nanoparticle can be detected.
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| http://dx.doi.org/10.1016/j.fertnstert.2007.08.021 | DOI Listing |
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