Objective: To describe the first case of IVF pregnancy in a pancreas-kidney recipient.
Design: Case report.
Setting: Reproductive Medicine Department, Hôpital Edouard Herriot, Lyon, France.
Intervention(s): In vitro fertilization in a pancreas-kidney recipient.
Patient(s): A 39 year-old nulliparous woman, with primary infertility and a history of pancreas-kidney transplant at 29 years of age.
Main Outcome Measure(s): Multidisciplinary agreement for the couple to be managed by IVF. Follow-up of pregnancy and delivery.
Result(s): Singleton IVF pregnancy in a pancreas-kidney recipient, maintained up to 34 weeks. Cesarian delivery ahead of labor. No severe maternal or fetal complications. Live birth. Normal postpartum renal function and glycemia.
Conclusion(s): An IVF pregnancy is feasible in a pancreas-kidney recipient. Such treatment should follow agreement by all the medical teams following the patient. Pregnancy in a pancreas-kidney recipient is at-risk, requiring close monitoring.
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http://dx.doi.org/10.1016/j.fertnstert.2007.08.038 | DOI Listing |
Transplantation
January 2025
Faculty of Medicine and Health, University of Sydney Medical School, University of Sydney, Sydney, NSW, Australia.
Background: Simultaneous pancreas-kidney (SPK) transplantation is an effective treatment option for type 1 diabetes mellitus and concurrent end-stage kidney disease. However, the diabetogenic effects of immunosuppression can counteract the beneficial effects of sustained normoglycemia. Long-term metabolic trends that reflect cardiovascular risk are reported poorly in the literature.
View Article and Find Full Text PDFTransplant Proc
January 2025
Unit of Hepatobiliary Surgery and Liver Transplantation, University Hospital of Padua, Padua, Italy; Dipartimento di Medicina di Precisione e Rigenerativa e Area Jonica (DiMePRe-J) Bari University; Department of Surgery, Yale University School of Medicine, New Haven, Connecticut. Electronic address:
Background: Liver transplantation (LT) is the main indication for the treatment of end-stage liver disease but have to face organ shortages. Using marginal donors is an option to increase the donor pool. Previous studies showed that the graft procured using N-acetylcysteine (NAC) provides a longer survival compared to perfusion with standard solutions, especially in marginal liver donors.
View Article and Find Full Text PDFIntroduction: The management of urinary tract stones, particularly kidney allograft stones, presents unique challenges for kidney transplant recipients because of their prevalence and specific clinical considerations. Here, we describe a case in which percutaneous nephrolithotomy was successfully used to fragment a large kidney allograft stone ≥20 mm in size.
Case Presentation: A 57-year-old woman who underwent ureteroureterostomy post simultaneous pancreas-kidney transplantation presented with gross hematuria after 15 years.
Transpl Int
January 2025
Department of Nephrology, University Hospital Zurich, Zurich, Switzerland.
Surg Obes Relat Dis
December 2024
Division of Transplantation, Department of Surgery, University of Minnesota, Minneapolis, Minnesota.
Background: The clinical impact of bariatric surgery (BS) prior to pancreas transplantation (PTx) is unclear.
Setting: University of Minnesota Hospital, Minneapolis, MN.
Methods: This was a single center retrospective case-controlled study of all patients January 1, 1998 and May 1, 2024 with a history of BS prior to PTx.
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