Two hundred fifteen compounds isolated from plants of Northeastern Brazil flora have been assayed against epimastigote forms of Trypanosoma cruzi, using the tetrazolium salt MTT as an alternative method. Eight compounds belonging to four different species: Harpalyce brasiliana (Fabaceae), Acnistus arborescens and Physalis angulata (Solanaceae), and Cordia globosa (Boraginaceae) showed significant activity. Among them, a novel and a known pterocarpan, a chalcone, four withasteroids, and a meroterpene benzoquinone were the represented chemical classes.
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http://dx.doi.org/10.1016/j.bmc.2007.11.027 | DOI Listing |
Microb Ecol
December 2024
Faculty of Agricultural, Environmental and Food Sciences, Free University of Bozen-Bolzano, Bolzano, Italy.
The gut microbiome plays an important role in insect evolution and ecology. Bacteria support the host's nutrition and defense and therefore play an important role in the fitness of the host. Halyomorpha halys is one of the most important invasive pest species in the world.
View Article and Find Full Text PDFNat Prod Res
December 2024
Department of Nuclear Medicine, General Hospital of Northern Theater Command, Shenyang, Liaoning, China.
(), known for its aromatic leaves and rhizomes, is extensively used in traditional medicine to treat digestive issues, inflammation, pain, anxiety, and stress. The petroleum ether extract of isolates specific bioactive compounds using petroleum ether, a nonpolar solvent effective in dissolving nonpolar plant compounds. This extract potentially offers antimicrobial, anti-inflammatory, and analgesic benefits.
View Article and Find Full Text PDFHum Genet
December 2024
Department of Pharmacy and Biotechnology, University of Bologna, 40126, Bologna, Italy.
Recent thermodynamic and functional studies have been conducted to evaluate the impact of amino acid substitutions on Calmodulin (CaM). The Critical Assessment of Genome Interpretation (CAGI) data provider at University of Verona (Italy) measured the melting temperature (T) and the percentage of unfolding (%unfold) of a set of CaM variants (CaM challenge dataset). Thermodynamic measurements for the equilibrium unfolding of CaM were obtained by monitoring far-UV Circular Dichroism as a function of temperature.
View Article and Find Full Text PDFFront Pharmacol
December 2024
Laboratory of Bioressources, Biotechnology, Ethnopharmacology and Health, Faculty of Sciences, Mohammed First University, Oujda, Morocco.
[This corrects the article DOI: 10.3389/fphar.2024.
View Article and Find Full Text PDFFront Plant Sci
December 2024
College of Forestry, The Northeast Forestry University, Harbin, China.
Global warming has significantly altered plant phenology by advancing the timing of leaf emergence, impacting vegetation productivity and adaptability. Winter and spring temperatures have commonly been used to explain spring phenology shifts, but we still lack a solid understanding of the effects of interactions between conditions in different seasons. This study utilizes normalized difference vegetation index (NDVI) and meteorological data to examine the effects of changes in winter and spring temperatures and precipitation on the start of the vegetation growing season (SOS) at high latitudes in China from 1982 to 2015.
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