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Association of genetically proxied cancer-targeted drugs with cardiovascular diseases through Mendelian randomization analysis.
J Transl Med
January 2025
Department of Cardiology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Background: Cancer-targeted therapies are progressively pivotal in oncological care. Observational studies underscore the emergence of cancer therapy-related cardiovascular toxicity (CTR-CVT), impacting patient outcomes. We aimed to investigate the causal relationship between different types of cancer-targeted therapies and cardiovascular disease (CVD) outcomes through a two-sample Mendelian randomization (MR) study.
View Article and Find Full Text PDFComparison of the value of transvaginal ultrasonography and MRI in the diagnosis of cesarean scar pregnancy: a meta-analysis.
J Matern Fetal Neonatal Med
December 2025
Department of Ultrasound, the First Affiliated Hospital of Hainan Medical College, Haikou, Hainan, China.
Objective: To compare the diagnostic value of transvaginal ultrasound (TVS) and magnetic resonance imaging (MRI) in cesarean scar pregnancy (CSP) by a method of meta-analysis.
Methods: Studies on TVS and MRI for CSP were collected from PubMed, Cochrane Library, Embase, Web of Science, China National Knowledge Infrastructure (CNKI), Wanfang data, and Chinese Scientific Journal Database (VIP database) until April 1, 2024. Stata 15.
The impact of sexual behavior on facial skin aging and pigmentation: evidence from Mendelian randomization and Bayesian colocalization analyses.
Arch Dermatol Res
January 2025
Department of Urology, The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, 730030, Gansu, China.
Editorial: Climate change is a children's health hazard.
Environ Res Health
October 2024
Pediatrics, Emory University School of Medicine, Atlanta, GA, United States of America.
As temperatures defy heat records, it is difficult to ignore the implications of climate change for public health, including impacts on population health more specifically. In short, climate change is happening now and presents an immediate hazard to human health on a global scale. Age-related health effects are an inalienable truth; physiology is relatively universal, and so are the ways in which our bodies respond to different types and levels of exposures to environmental stressors at different lifestages.
View Article and Find Full Text PDFEfficacy of Enhanced Rehabilitation Initiated After Hospital Discharge to Improve Quality of Life in Survivors of Critical Care: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Cureus
December 2024
Department of Emergency and Critical Care Medicine, Wakayama Medical University, Wakayama, JPN.
Article Synopsis
- This systematic review and meta-analysis assessed how enhanced rehabilitation after hospital discharge affects the quality of life (QOL) for survivors of critical care, following PRISMA guidelines and examining data from several major health databases until January 2024.
- The review included nine randomized controlled trials (RCTs) with 573 participants, finding that enhanced rehabilitation showed no significant improvement in physical QOL but did result in a higher mental QOL score (low-certainty evidence).
- Adverse events' impact was uncertain, with mixed reports from the studies; some had no adverse events, while others noted serious incidents, indicating very low-certainty evidence on this issue.
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