This paper introduces a new method for navigated spine surgery using a stereoscopic video see-through head-mounted display (HMD) and an optical tracking system. Vertebrae are segmented from volumetric CT data and visualized in-situ. A surgical drilling device is virtually extended with a mirror for intuitive planning of the drill canal, control of drill direction and insertion depth. The first designated application for the virtually extended drilling device is the preparation of canals for pedicle screw implantation in spine surgery. The objective of surgery is to install an internal fixateur for stabilization of injured vertebrae. We invited five surgeons of our partner clinic to test the system with realistic replica of lumbar vertebrae and compared the new approach with the classical, monitor-based navigation system providing three orthogonal slice views on the operation site. We measured time of procedure and scanned the drilled vertebrae with CT to verify accuracy of drilling.
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http://dx.doi.org/10.1007/978-3-540-75757-3_53 | DOI Listing |
Unlabelled: Motivated behaviors are regulated by distributed forebrain networks. Traditional approaches have often focused on individual brain regions and connections that do not capture the topographic organization of forebrain connectivity. We performed co-injections of anterograde and retrograde tract tracers in rats to provide novel high-spatial resolution evidence of topographic connections that elaborate a previously identified closed-loop forebrain circuit implicated in affective and motivational processes.
View Article and Find Full Text PDFJ Phys Chem Lett
January 2025
Physical Science and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia.
Materials exhibiting both metallic and semiconducting states, including two-dimensional transition metal dichalcogenides (TMDs), have numerous applications. We therefore investigate the effects of axial and shear strains on the phase energetics of pristine and striped TMDs using density functional theory and classical molecular dynamics simulations. We demonstrate that control of the phase distribution can be achieved by the integration of strain engineering and Kirigami techniques.
View Article and Find Full Text PDFComput Struct Biotechnol J
December 2024
Department of Computer Science, Virginia Commonwealth University, Richmond, VA 23284, USA.
A large portion of the Intrinsically Disordered Regions (IDRs) in protein sequences interact with proteins, nucleic acids, and other types of ligands. Correspondingly, dozens of sequence-based predictors of binding IDRs were developed. A recently completed second community-based Critical Assessments of protein Intrinsic Disorder prediction (CAID2) evaluated 32 predictors of binding IDRs.
View Article and Find Full Text PDFSci Rep
December 2024
BAOBAB Unit, NeuroSpin center, CEA, Université Paris-Saclay, Gif-sur-Yvette, France.
Decoding states of consciousness from brain activity is a central challenge in neuroscience. Dynamic functional connectivity (dFC) allows the study of short-term temporal changes in functional connectivity (FC) between distributed brain areas. By clustering dFC matrices from resting-state fMRI, we previously described "brain patterns" that underlie different functional configurations of the brain at rest.
View Article and Find Full Text PDFNeurobiol Learn Mem
January 2025
Faculty of Science, Hokkaido University Sapporo 060-0810, Japan; Research Institute for Electronic Science, Hokkaido University, Sapporo 060-0812, Japan. Electronic address:
Social learning, learning from other individuals, has been demonstrated in many animals, including insects, but its detailed neural mechanisms remain virtually unknown. We showed that crickets (Gryllus bimaculatus) exhibit aversive social learning with a dead conspecific. When a learner cricket was trained to observe a dead cricket on a drinking apparatus, the learner avoided the odor of that apparatus thereafter.
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