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Understanding the role of metabolic syndrome in prostate cancer risk: A UK Biobank prospective cohort study.
Sci Rep
January 2025
Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.
Predictive value of metabolic syndrome for prostate cancer risk is not clear. We aimed to assess the association between metabolic syndrome and its components with prostate cancer incidence. The primary outcome was prostate cancer incidence, i.
View Article and Find Full Text PDFIs a syndromic approach well suited to foodborne disease surveillance? Implication for salmonellosis surveillance and prevention in France from a "One Health" perspective.
Prev Vet Med
January 2025
University of Lyon - French Agency for Food, Environmental and Occupational Health & Safety (ANSES), Laboratory of Lyon, Epidemiology and support to Surveillance Unit, Lyon, France. Electronic address:
In response to the increasing emergence of zoonotic pathogens, flexible, multisectoral surveillance systems capable of generating alerts thanks to rapid, nonspecific detection, are crucial before pathogens reach human populations. Syndromic surveillance has proven to be a breakthrough for near real-time disease surveillance in the public health sector. It relies on existing nonspecific data, usually collected for other purposes.
View Article and Find Full Text PDFUse of the flexible vacuum-assisted ureteral access sheath combined with flexible ureteroscope for patients with large renal stones.
Am J Transl Res
December 2024
Department of Urinary Surgery, Jiashan County Chinese Medicine Hospital Jiaxing, Zhejiang, China.
Objective: To explore the effects and safety of the flexible vacuum-assisted ureteral access sheath combined with a flexible ureteroscope for the treatment of large renal stones over 3 cm.
Methods: In this retrospective study, 122 patients with kidney stones (stone diameter ≥ 3 cm) admitted to our hospital from January 2018 to December 2022 were selected as the study subjects. According to different surgical methods, these patients were divided into an observation group and a control group, with 61 cases in each group.
Why and how should we simulate platform trials? Learnings from EU-PEARL.
BMC Med Res Methodol
January 2025
Center for Medical Data Science, Medical University of Vienna, Spitalgasse 23, Vienna, 1090, Austria.
Background: Platform trials are innovative clinical trials governed by a master protocol that allows for the evaluation of multiple investigational treatments that enter and leave the trial over time. Interest in platform trials has been steadily increasing over the last decade. Due to their highly adaptive nature, platform trials provide sufficient flexibility to customize important trial design aspects to the requirements of both the specific disease under investigation and the different stakeholders.
View Article and Find Full Text PDFCost Effectiveness of Colorectal Cancer Screening Strategies in Middle- and High-Income Countries: A Systematic Review.
J Gastroenterol Hepatol
January 2025
Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Background And Aim: Colorectal cancer (CRC) is a significant global health burden, and screening can greatly reduce CRC incidence and mortality. Previous studies investigated the economic effects of CRC screening. We performed a systematic review to provide the cost-effectiveness of CRC screening strategies across countries with different income levels.
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