On July 1, 2006, the Medical University of Ohio officially merged with the University of Toledo and became the third largest public institution of higher education in the state of Ohio. The combination of the two neighboring institutions occurred through the efforts of a number of individuals who recognized the potential advantages of a merger and worked quickly through challenges by early engagement of stakeholders in the merger process. The advantages of a larger, more diverse institution with increased budget and research funding outweighed the challenges of bringing two different cultures together. Changing the culture and leadership was necessary to allow the process to move forward. In addition, statewide political support was mobilized to carry forward the legislative actions that permitted the formation of the new institution. The transformation of a free standing medical campus to a part of a larger university required a fusion of the existing boards of trustees, a new organizational structure and a unified strategic plan, all of which occurred in the first 12 months after the merger. The college of medicine of the former Medical University of Ohio has been strengthened by the merger process, and the new University of Toledo has emerged as a much more diverse and complete institution.
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http://dx.doi.org/10.1097/ACM.0b013e318159e2b8 | DOI Listing |
Chimeric antigen receptor (CAR) T-cell products axicabtagene ciloleucel (axi-cel), tisagenlecleucel (tisa-cel), and lisocabtagene maraleucel (liso-cel) are approved for relapsed/refractory large B-cell lymphoma (R/R LBCL). Emerging evidence indicates that delayed CAR T-cell infusion, including prolonged time from leukapheresis to infusion, known as vein-to-vein time (V2Vt), may adversely impact clinical outcomes. We conducted a systematic literature review (SLR) and meta-analysis to identify differences in V2Vt in patients with R/R LBCL treated with axi-cel, tisa-cel, or liso-cel.
View Article and Find Full Text PDFBlood Adv
January 2025
Vanderbilt University Medical Center, Nashville, Tennessee, United States.
In plasma, the zymogens factor XII (FXII) and prekallikrein reciprocally convert each other to the proteases FXIIa and plasma kallikrein (PKa). PKa cleaves high-molecular-weight kininogen (HK) to release bradykinin, which contributes to regulation of blood vessel tone and permeability. Plasma FXII is normally in a "closed" conformation that limits activation by PKa.
View Article and Find Full Text PDFCirculation
January 2025
University of Texas Southwestern Medical Center, Dallas (D.K.M, J.A.d.L., J.A.H).
J Med Internet Res
January 2025
Department High-Tech Business and Entrepreneurship Section, Industrial Engineering and Business Information Systems, University of Twente, Enschede, Overijssel, Netherlands.
Health recommender systems (HRS) have the capability to improve human-centered care and prevention by personalizing content, such as health interventions or health information. HRS, an emerging and developing field, can play a unique role in the digital health field as they can offer relevant recommendations, not only based on what users themselves prefer and may be receptive to, but also using data about wider spheres of influence over human behavior, including peers, families, communities, and societies. We identify and discuss how HRS could play a unique role in decreasing health inequities.
View Article and Find Full Text PDFJ Med Internet Res
January 2025
International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Tsukuba, Ibaraki, Japan.
Background: Few studies have explored the relationship between macronutrient intake and sleep outcomes using daily data from mobile apps.
Objective: This cross-sectional study aimed to examine the associations between macronutrients, dietary components, and sleep parameters, considering their interdependencies.
Methods: We analyzed data from 4825 users of the Pokémon Sleep and Asken smartphone apps, each used for at least 7 days to record objective sleep parameters and dietary components, respectively.
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