AI Article Synopsis
- The study examines the use of the argyrophil staining technique for NOR proteins (Ag-NORs) in differentiating between atypical hyperplasia and well-differentiated carcinoma in endometrial lesions.
- The Ag-NOR count showed that endometrial carcinoma had higher counts compared to atypical hyperplastic endometrium.
- However, the overlap in Ag-NOR values between the two conditions suggests that this method might not be reliable for making a definitive diagnosis.
Article Abstract
In the current study the argyrophil staining technique for NOR proteins (Ag-NORs) has been performed on cases of different endometrial lesions, trying to find an aid in differentiating atypical hyperplasia from well differentiated carcinoma in biopsy specimens. We conclude that the Ag-NOR count, even though in endometrial carcinoma is significantly exceeding that of atypical hyperplastic endometrium, could be a misleading discriminator, because of a wide overlap of values in individual cases.
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