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A Case Study on EEG Signal Correlation Towards Potential Epileptic Foci Triangulation.
Sensors (Basel)
December 2024
Nencki Institute of Experimental Biology of the Polish Academy of Sciences, 02-093 Warsaw, Poland.
The precise localization of epileptic foci with the help of EEG or iEEG signals is still a clinical challenge with current methodology, especially if the foci are not close to individual electrodes. On the research side, dipole reconstruction for focus localization is a topic of recent and current developments. Relatively low numbers of recording electrodes cause ill-posed and ill-conditioned problems in the inversion of lead-field matrices to calculate the focus location.
View Article and Find Full Text PDFPolymeric Materials Used in 3DP in Dentistry-Biocompatibility Testing Challenges.
Polymers (Basel)
December 2024
Department of Professional Organization and Medical Legislation-Malpractice, "Carol Davila" University of Medicine and Pharmacy, 17-23 Plevnei Street, 020021 Bucharest, Romania.
In the latter part of the 20th century, remarkable developments in new dental materials and technologies were achieved. However, regarding the impact of dental resin-based materials 3D-printed on cellular responses, there have been a limited number of published studies recently. The biocompatibility of dental restorative materials is a controversial topic, especially when discussing modern manufacturing technologies.
View Article and Find Full Text PDFGlobal Trends and Hotspots in Non-Targeted Screening of Water Pollution Research: Bibliometric and Visual Analysis.
Toxics
November 2024
Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200336, China.
Non-targeted screening (NTS) technology has been showing significant potential in identifying contaminants of emerging concern (CECs) in water and has attracted great attention in academia in recent years. It is a method that analyzes samples without pre-selecting substances, enabling the detection and identification of unknown compounds, which is crucial for environmental health and public protection. This study uses the Bibliometrix package in R 4.
View Article and Find Full Text PDFMultidrug and Toxic Compound Extrusion Transporters: Ubiquitous Multifaceted Proteins in Microbes, Plants, and Their Interactions.
Microorganisms
November 2024
Laboratorio di Patologia Vegetale Molecolare, Dipartimento di Scienze e Tecnologie Agrarie, Alimentari Ambientali e Forestali, Università degli Studi di Firenze, Via della Lastruccia 10, 50019 Sesto Fiorentino, Firenze, Italy.
In recent years, membrane transporters have attracted considerable interest regarding their involvement in the molecular dialogue occurring between microbes and their hosts. In particular, the multidrug and toxic compound extrusion (MATE) transporters form a family of integral membrane proteins, mainly involved in the efflux of toxic and xenobiotic compounds. They are present in all living organisms, both prokaryotes and eukaryotes, where they have a wide array of extremely different roles.
View Article and Find Full Text PDFLatest Therapeutical Approaches for Triple-Negative Breast Cancer: From Preclinical to Clinical Research.
Int J Mol Sci
December 2024
Research Group of Cancer Biomarkers, Biomedical Research Institute of Lleida (IRBLleida), Av. Alcalde Rovira Roure, 80, 25198 Lleida, Spain.
Triple-negative breast cancer (TNBC) represents roughly one-sixth of all breast cancer patients, but accounts for 30-40% of breast cancer deaths. Due to the lack of typical biomarkers exploited clinically for breast cancer, it remains very difficult to treat. Moreover, its intrinsic high heterogeneity and proneness to become resistant to the drugs administered makes the treatment management very challenging for oncologists.
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