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Rationale and design of the beta-blockers in tako-tsubo syndrome study: a randomized clinical trial (β-Tako).
Rev Esp Cardiol (Engl Ed)
December 2024
Center of Excellence of Cardiovascular Sciences, Ospedale Isola Tiberina - Gemelli Isola, Catholic University of the Sacred Heart, Rome, Italy.
Introduction Y Objectives: Tako-tsubo syndrome (TTS) is a cardiac condition that mimics acute coronary syndrome, characterized by transient left ventricular dysfunction in the absence of culprit coronary artery stenosis. Although its etiology remains unknown, reversible microvascular dysfunction secondary to an adrenergic surge is thought to play a role. Treatment is empirical, although most patients receive beta-blockers (BB) in clinical practice.
View Article and Find Full Text PDFAtypical Takotsubo Post-Natural Delivery: A Guideline-Based Approach for Diagnosing Takotsubo Cardiomyopathy.
Cureus
November 2024
Cardiology, Eastbourne District General Hospital, East Sussex Healthcare NHS Trust, Eastbourne, GBR.
Since its first description in 1990, Takotsubo cardiomyopathy (TC) has continued to puzzle physicians and scientists alike as the mechanisms behind the characteristic unique left ventricular dysfunction that marks the condition and its relation to the intense emotional and physiological stressors that usually precede it have remained not fully understood. Since then, several different variants of the condition have been described that do not conform to the conventional narrative of a post-menopausal disease that only affects women of a certain age and is triggered by a preceding event. Of these variants, atypical Takotsubo, which does not assume the typical characteristic apical ballooning that marks the condition has been linked with a younger age group and a more neurological trigger.
View Article and Find Full Text PDFTakotsubo syndrome: Impact of medical therapies on prognosis. A state of art review.
Curr Probl Cardiol
August 2024
Division of Cardiology, Cardiovascular and Thoracic Department, "Citta della Salute e della Scienza" Hospital, Turin, Italy; Department of Medical Sciences, University of Turin, Turin, Italy.
Tako-Tsubo syndrome (TTS) presents as transient ventricular dysfunction, yet its underlying pathophysiology remains enigmatic. The prognosis of patients presenting with TTS appears to be impaired as compared to the general population and is similar to patients with acute coronary syndromes. Recent investigations have predominantly focused on elucidating therapeutic strategies associated with improved outcomes, particularly among post-menopausal female patients.
View Article and Find Full Text PDFBroken Heart: A Clear Case of Takotsubo Cardiomyopathy.
Cureus
November 2023
Emergency Department, Hamad Medical Corporation, Doha, QAT.
Takotsubo cardiomyopathy (TC) is a recognized clinical syndrome characterized by reversible cardiomyopathy with a distinctive left ventricular apical ballooning appearance. TC is associated with risk factors such as estrogen deficiency, emotional and physical stress, and genetic factors. The clinical presentation of TC can be like that of a myocardial infarction.
View Article and Find Full Text PDFEditorial: Cancer treatment-related cardiovascular disease - real world data in cardio-oncology.
Front Oncol
September 2023
Duke Cancer Institute, School of Medicine, Duke University, Durham, NC, United States.
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