Morphologic and microbiologic study of the operation and biopsy specimens, obtained from 73 patients with odontogenic inflammatory processes has shown that in 38% of cases the inflammation was induced by mixed fungal and bacterial flora. Associations of staphylococci or streptococci with actinomyces, Candida, Penicillium, Rhodotorula were most frequently isolated. As a rule, weak patients developed odontogenic inflammatory processes with mycotic involvement, these processes often taking a chronic course. Qualitative composition of the fungal-and-bacterial associations should be borne in mind when planning therapeutic measures for such patients.
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Georgian Med News
November 2024
1Faculty of Dentistry, Azerbaijan Medical University, Baku, Azerbaijan.
Background: Odontogenic cysts, generally classified as inflammatory or developmental, in dental practice are usually identified incidentally, on routine exams and constitute an important aspect of oral and maxillofacial pathology. A few literature sources provide epidemiological data on odontogenic cysts and tumors. However, these findings may help us to better understand such lesions and improve the diagnosis of odontogenic cysts and tumors.
View Article and Find Full Text PDFInt J Mol Sci
December 2024
Department of Pharmacy, "G. d'Annunzio" University of Chieti-Pescara, Via dei Vestini 31, 66100 Chieti, Italy.
Dental inflammatory diseases remain a challenging clinical issue, whose causes and development are still not fully understood. During dental caries, bacteria penetrate the tooth pulp, causing pulpitis. To prevent pulp necrosis, it is crucial to promote tissue repair by recruiting immune cells, such as macrophages, able to secrete signal molecules for the pulp microenvironment and thus to recruit dental pulp stem cells (DPSCs) in the damaged site.
View Article and Find Full Text PDFJ Oral Facial Pain Headache
March 2024
Department of Endodontics, Faculty of Odontology, Malmö University, 205 06 Malmö, Sweden.
To compare pain characteristics, impact of pain and characteristics of patients with painful root-filled teeth with and without signs of inflammatory dental disease. This cross-sectional study was performed in the Public Dental Health services, Region Örebro County, Sweden. Adult patients with ≥1 root-filled tooth identified at their regular check-up were included and assigned to one of two groups; those with ≥1 sign of inflammatory dental disease (DD+) and those without any such sign (DD-).
View Article and Find Full Text PDFBiomedicines
November 2024
Department of Odontotherapy and Endodontics, Faculty of Dental Medicine, "Victor Babes" University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square 2, 300041 Timisoara, Romania.
Odontogenic infections (OIs) can progress rapidly and may lead to severe systemic complications, especially in patients with underlying conditions like diabetes mellitus (DM). This study aims to evaluate the predictive value of inflammatory scores-quick Sequential Organ Failure Assessment (qSOFA), Systemic Immune-Inflammation Index (SII), derived Neutrophil-to-Lymphocyte Ratio (dNLR), and Odontogenic Infection Severity Score (OISS)-in assessing the severity of OIs in diabetic versus non-diabetic patients. A case-control study was conducted on 123 patients diagnosed with OIs.
View Article and Find Full Text PDFJ Stomatol Oral Maxillofac Surg
January 2025
Postgraduate Program in Dental Sciences, Department of Dentistry, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.
Introduction: Osteomyelitis is an inflammatory condition of the bone with a multifactorial etiology, including trauma and odontogenic infections. Despite being a common condition in clinical practice, limited research exists on the clinical and pathological profile of Osteomyelitis of the Jaws (OJ). This 51-year retrospective study aimed to describe the clinical, radiographic, and histopathological features of OJ diagnosed at a single oral pathology referral center.
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