The authors relate the principles according to which the individualized treatment of bronchial asthma patients may be organized: the permanent treating physician, active participation of the patient in the process of treatment, flexibility of the individualized complex of treatment measures under constant control of the treatment efficacy. Provide the experience gained with such organization of the treatment of 35 patients with grave bronchial asthma ("schools for bronchial asthma patients").
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In utero exposure to experimental maternal asthma alters fetal airway development in sheep.
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The mechanisms linking maternal asthma (MA) exposure in utero and subsequent risk of asthma in childhood are not fully understood. Pathological airway remodelling, including reticular basement membrane thickening, has been reported in infants and children who go on to develop asthma later in childhood. This suggests altered airway development before birth as a mechanism underlying increased risk of asthma in children exposed in utero to MA.
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