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Bioactive silicon-based dental gel associated with a calcium booster for dentin hypersensitivity treatment: A randomized clinical study.
J Clin Exp Dent
December 2024
Triplet Biotechnology Solutions, Inc., Bauru, SP, Brazil.
Background: Dentin hypersensitivity affects a significant portion of the world's population, causing pain and negatively impacting oral health and quality of life This clinical study investigated the effectiveness of a desensitizing fluoride silicon-rich dental gel associated with a calcium booster.
Material And Methods: In this single-blind, randomized, parallel-group clinical trial, forty-eight volunteers diagnosed with dentin hypersensitivity and qualified to participate were randomized into 2 groups: (1) fluoride silicon-rich dental gel (REFX Technology)/calcium booster (Si/Ca protocol); (2) Pumice stone diluted in saline. A draw was carried out between the right and left sides of the patients so that either a prophylaxis with the dental gel associated with calcium or with fine pumice stone diluted in saline was carried out.
Ivermectin moxidectin for treating infection: a systematic review.
Parasitology
January 2025
Health Technology Assessment Unit, Hospital Universitario Ramón y Cajal and Universidad de Alcalá (IRYCIS), CIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain.
The aim was to assess the efficacy of ivermectin moxidectin for treating infection. Ovid MEDLINE, Embase and Web of Science databases were searched for studies comparing ivermectin and moxidectin from inception to February 2024. The outcomes: elimination of infection or parasitological cure, mortality and serious adverse events.
View Article and Find Full Text PDFExploring potentially synthetic genes related to diarrhetic shellfish toxins production in Prorocentrum sp. via comparative transcriptomics.
Ecotoxicol Environ Saf
January 2025
College of Life Science and Technology, and Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Jinan University, Guangzhou 510362, China. Electronic address:
Harmful algal blooms (HABs), exacerbated by climate change and environmental disturbances, pose global challenges due to marine toxin contamination, particularly diarrhetic shellfish toxins (DSTs). DSTs are prevalent marine toxins, and understanding their synthesis is vital for managing fisheries and mitigating environmental triggers. This study delves into the synthesis mechanisms of DSTs in Prorocentrum arenarium and Prorocentrum lima, which vary in toxin types and concentrations.
View Article and Find Full Text PDFRu-Morpholine-Derived Thiosemicarbazone-Based Metallodrugs: Lysosome-Targeted Anticancer Agents.
ACS Appl Bio Mater
January 2025
Department of Chemistry, National Institute of Technology, Rourkela, Odisha 769008, India.
The idea of coordinating biologically active ligand systems to metal centers to exploit their synergistic effects has gained momentum. Therefore, in this report, three Ru complexes - of morpholine-derived thiosemicarbazone ligands have been prepared and characterized by spectroscopy and HRMS along with the structure of through a single-crystal X-ray diffraction study. The solution stability of - was tested using conventional techniques such as UV-vis and HRMS.
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