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Effect of Planting Systems on the Physicochemical Properties and Bioactivities of Strawberry Polysaccharides.
Foods
January 2025
College of Food Science and Engineering, Guiyang University, Guiyang 550005, China.
Suitable planting systems are critical for the physicochemical and bioactivities of strawberry ( Duch.) polysaccharides (SPs). In this study, SPs were prepared through hot water extraction, and the differences in physicochemical characteristics and bioactivities between SPs derived from elevated matrix soilless planting strawberries (EP-SP) and those from and conventional soil planting strawberries (GP-SP) were investigated.
View Article and Find Full Text PDFImpact of High Glucose on Bone Collagenous Matrix Composition, Structure, and Organization: An Integrative Analysis Using an Ex Vivo Model.
Cells
January 2025
Laboratory for Bone Metabolism and Regeneration, Faculty of Dental Medicine, University of Porto, 4200-393 Porto, Portugal.
Diabetes mellitus is a widespread metabolic disorder linked to numerous systemic complications, including adverse effects on skeletal health, such as increased bone fragility and fracture risk. Emerging evidence suggests that high glucose may disrupt the extracellular matrix (ECM) of bone, potentially altering its composition and organization. Collagen, the primary organic component of the ECM, is critical for maintaining structural integrity and biomechanical properties.
View Article and Find Full Text PDFEnhancing shelf-life of dried goji berry: Effects of drying methods and packaging conditions on browning evolution.
Food Res Int
February 2025
College of Engineering, China Agricultural University, P.O. Box 194, 17 Qinghua Donglu, Beijing 100083, China. Electronic address:
Preservation and shelf-life extension are of paramount importance for dried goji berry, especially those dehydrated using pulsed vacuum drying (PVD), which are generally applied for the high-quality dried products in the markets. This study compared the storage stability of dried goji berry dehydrated using PVD versus conventional hot wind drying (HWD), focusing on the complex interactions between packaging conditions and physicochemical compounds during accelerated storage. The results showed that PVD-dried goji berry exhibited higher browning degree (2.
View Article and Find Full Text PDFIn Vivo UV-Induced Fluorescence Spectroscopy of Skin in Parkinson's Disease.
Dokl Biol Sci
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Research Center of Neurology, Moscow, Russia.
Characteristic patterns of UV-induced skin autofluorescence were determined for patients with Parkinson's disease (PD) and associated with dysmetabolic alterations, such as nonenzymatic protein glycation, an increase in extracellular matrix stiffness, impaired metabolism of tissue fluorophores, mitochondrial dysfunction, and accumulation of aberrant proteins. Key differences in skin autofluorescence spectra were for the first time observed in PD, making it possible to discriminate between PD patients and healthy persons or individuals without signs of chronic neurodegeneration. Namely, skin fluorescence related to the reflected signal upon excitation with UV light at 375 nm was lower in PD patients.
View Article and Find Full Text PDFThe molecular basis of Human FN3K mediated phosphorylation of glycated substrates.
Nat Commun
January 2025
Cold Spring Harbor Laboratory, One Bungtown Road, Cold Spring Harbor, New York, 11724, USA.
Glycation, a non-enzymatic post-translational modification occurring on proteins, can be actively reversed via site-specific phosphorylation of the fructose-lysine moiety by FN3K kinase, to impact the cellular function of the target protein. A regulatory axis between FN3K and glycated protein targets has been associated with conditions like diabetes and cancer. However, the molecular basis of this relationship has not been explored so far.
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