As U.S. life expectancy has increased, questions arise as to how the quality of health and functioning in the elderly population has changed. Data from the 1982-2004 National Long-Term Care Survey (NLTCS) suggested that chronic disability prevalence above age 65 declined at an increasing rate with a 2.2% per annum rate of decline from 1999 to 2004 ( 71 ). Inflation-adjusted per capita Medicare expenditure rates in nondisabled persons also declined, 0.9% per annum from 1982 to 2004, which suggests that declines in disability were driven by improving health -- not by increases in per capita health expenditures. Declines in disability prevalence were found in other U.S. national health surveys. Analyses of U.S. Civil War veterans suggest recent disability declines were continuations of declines in both chronic disease and disability occurring over the past century due to improved nutrition, sanitation, and education. Concerns exist about whether disability declines will continue because of recent increases in obesity prevalence.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1146/annurev.publhealth.29.020907.090812 | DOI Listing |
J Dent Sci
January 2025
Department of Oral Hygiene, College of Dental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Background/purpose: Dentists often focus on masticatory performance (MP) rather than masticatory ability (MA) and treatment expectations when evaluating older adults. This study aimed to determine if MA aligns with MP and to explore influencing factors.
Materials And Methods: This cross-sectional study utilized a multi-stage stratified cluster sampling, including one thousand community-dwelling adults aged 60 and older.
J Dent Sci
January 2025
Department of Oral Physiology, School of Dentistry, Seoul National University, Seoul, Republic of Korea.
Background/purpose: Chronic periodontitis and tooth loss contribute to cognitive decline. Since many biological processes are shared by loss of teeth and loss of pulps, this study investigated the potential association between loss of pulp and the development of dementia.
Materials And Methods: A retrospective cohort analysis was conducted to investigate the association between dental treatment and the development of dementia.
Open Forum Infect Dis
January 2025
Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
Background: Patients with kidney disease are at high risk for adverse outcomes after coronavirus disease 2019 (COVID-19) despite vaccination. Because patients with advanced chronic kidney disease (CKD) and kidney failure were excluded from registrational trials, the impact of the protease inhibitor nirmatrelvir-ritonavir in patients with kidney disease is unknown.
Methods: This was a cohort study evaluating adverse outcomes in patients with kidney disease who developed COVID-19.
Clin Kidney J
January 2025
Department of General Internal Medicine and Nephrology, Robert Bosch Hospital Stuttgart, Stuttgart, Germany.
Background: Sparsentan, a dual-acting antagonist for both the angiotensin II receptor type 1 and the endothelin receptor type A, has emerged as a promising therapeutic agent for the treatment of IgA nephropathy (IgAN). Following the publication of the PROTECT trial, sparsentan recently received approval for the treatment of IgAN in Europe. However, it remains uncertain whether an additive effect can be observed in the context of existing treatment with sodium-glucose co-transporter 2 (SGLT2) inhibitors, given that the PROTECT study did not investigate this dual therapy approach.
View Article and Find Full Text PDFLife Metab
October 2023
Department of Fundamental Oncology, University of Lausanne, 1007 Lausanne, Switzerland.
Aging represents an emerging challenge for public health due to the declined immune responses against pathogens, weakened vaccination efficacy, and disturbed tissue homeostasis. Metabolic alterations in cellular and systemic levels are also known to be cardinal features of aging. Moreover, cellular metabolism has emerged to provide regulations to guide immune cell behavior via modulations on signaling cascades and epigenetic landscape, and the aberrant aging process in immune cells can lead to inflammaging, a chronic and low-grade inflammation that facilitates aging by perturbing homeostasis in tissues and organs.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!