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A general strategy towards activatable nanophotosensitizer for phototoxicity-free photodynamic therapy.
Theranostics
January 2025
Biomaterials Research Center, School of Biomedical Engineering, Southern Medical University 510515, Guangzhou, Guangdong Province, China.
Photodynamic therapy (PDT) has gained widespread attention in cancer treatment, but it still faces clinical problems such as skin phototoxicity. Activatable photosensitizers offer a promising approach to addressing this issue. However, several significant hurdles need to be overcome, including developing effective activation strategies and achieving the optimal balance between photodynamic effects and related side effects.
View Article and Find Full Text PDFSynergistically Halogenated and Methoxylated Thiophene Additive Enables High-Performance Organic Solar Cells.
Small
January 2025
Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing, 400714, P. R. China.
Morphology control plays a key role for improving efficiency and stability of bulk heterojunctions (BHJ) organic solar cells (OSCs). Halogenation and methoxylation are two separate ways successfully adopted in additives for morphology optimization. In this work, these two strategies are combined together.
View Article and Find Full Text PDFNanoscale self-assembly and water retention properties of silk fibroin-riboflavin hydrogel.
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January 2025
Department of Systems and Computational Biology, School of Life Sciences, University of Hyderabad, Prof. C. R. Rao Road, Gachibowli, Hyderabad 500046, Telangana, India.
Silk-fibroin hydrogels have gained considerable attention in recent years for their versatile biomedical applications. The physical properties of a complex hydrogel, comprising silk fibroin and riboflavin, surpass those of the silk fibroin-hydrogel without additives. This study investigates silk fibroin-riboflavin (silk-RIB) hydrogel at the atomistic level to uncover molecular structures and chemical characteristics specific to silk fibroin and riboflavin molecules in an aqueous medium.
View Article and Find Full Text PDFComparative analysis of bone healing in subcritical defects with air turbine and electric handpiece in a rat model.
PLoS One
January 2025
Department of Diagnosis and Surgery, São Paulo State University (UNESP), School of Dentistry, Araçatuba, São Paulo, Brazil.
Rotatory devices are essential in clinical surgical practice, however, depending on the different systems available, their function can impact bone repair and postoperative responses on varying scales. This impact underscores the need to explore new techniques aiming to enhance bone repair. This study aimed to assess the immediate and delayed effects on bone healing in subcritical bone defects using both air turbine and an electric handpiece.
View Article and Find Full Text PDFElectrokinetic flow instabilities in shear thinning fluids with conductivity gradients.
Soft Matter
January 2025
Department of Mechanical Engineering, Clemson University, Clemson, SC 29634, USA.
Instabilities in the form of periodic or irregular waves at the fluid interface have been demonstrated in microchannel electrokinetic flows with conductivity gradients when the applied electric field is above a threshold value. Most prior studies on electrokinetic instabilities (EKI) are restricted to Newtonian fluids though many of the chemical and biological samples in microfluidic applications exhibit non-Newtonian characteristics. We present in this work an experimental study of the effects of fluid shear thinning on the development of EKI waves through the addition of a small amount of xanthan gum (XG) polymer to both the high- and low-concentration Newtonian buffer solutions.
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