Effect of intracranial injection of spermine on feeding and drinking behavior was studied in rats. A significant and long-term suppression of feeding and drinking behavior appeared when 30 nmol/hemisphere of spermine was bilaterally injected into the lateral hypothalamic area, substantia nigra or ventral noradrenergic bundle. Micro-injected spermine into the medial amygdaloid nucleus produced a weak and short-time but significant suppression of ingestive behavior. On the other hand, a significant increase in feeding and drinking behavior was observed when spermine was injected into the ventromedial hypothalamic nucleus. These results suggest that spermine inhibits neuronal activity of all the brain regions studied here.
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http://dx.doi.org/10.1248/bpb1978.14.407 | DOI Listing |
Sci Total Environ
January 2025
Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa 277-8563, Chiba, Japan; Atmosphere and Ocean Research Institute, The University of Tokyo, Kashiwa 277-8564, Chiba, Japan.
In recent decades, microplastics (MPs) have emerged as one of the biggest environmental challenges in aquatic environments. Ingestion and toxicity of MPs in seawater (SW) and freshwater (FW) fish have been studied extensively both in field and laboratory settings. However, the basic mechanism of how fish deal with MPs in SW and FW remains unclear, although physiological conditions of fish differ significantly in the two environments.
View Article and Find Full Text PDFJ Hum Nutr Diet
February 2025
School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Background: Meeting protein intake recommendations is relevant for maintaining muscle mass. This study aimed to describe protein intake and its association with meal patterns and dietary patterns.
Methods: An in-house designed, web-based 4-day record was used in the national dietary survey (in 2010/2011).
Hepatology
January 2025
Université Côte d'Azur, INSERM, U1065, C3M, Nice, France.
Background And Aims: Alcohol-related liver disease (ALD) is one of the leading causes of severe liver disease with limited pharmacological treatments for alcohol-related steatohepatitis (ASH). CD44, a glycoprotein mainly expressed in immune cells, has been implicated in multiple inflammatory diseases but has never been studied in the ALD context. We therefore studied its contribution to ASH development in mice and its expression in ALD patients.
View Article and Find Full Text PDFSci Total Environ
January 2025
Department of Civil, Geological, and Mining Engineering, Polytechnique Montreal, Montreal, QC H3C 3A7, Canada. Electronic address:
Understanding the dynamics of fecal bacterial communities is crucial for managing public health risks and protecting drinking water resources. While extensive research exists on how abiotic factors influence the survival of fecal microbial communities in water, less attention has been paid to the impact of predation by higher organisms, such as the widely distributed grazer Daphnia. Nevertheless, Daphnia plays a significant role in regulating bacterial communities in natural aquatic ecosystems, and recent studies highlighted its potential as a biofilter in alternative tertiary wastewater treatment systems.
View Article and Find Full Text PDFJ Indian Soc Pedod Prev Dent
October 2024
Department of Pedodontics and Preventive Dentistry, Sardar Patel Post Graduate Institute of Dental and Medical Sciences, Lucknow, Uttar Pradesh, India.
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