This study compared Autism diagnostic observation schedule (ADOS) algorithm scores of a sample of 26 children who were administered modules 1-3 of the ADOS with the scores obtained applying the revised ADOS algorithm proposed by Gotham et al. (2007). Results of this application were inconsistent, yielding slightly more accurate results for module 1. New algorithm scores on modules 2 and 3 remained consistent with the original algorithm scores. The Mann-Whitney U was applied to compare revised algorithm and clinical levels of social impairment to determine if significant differences were evident. Results of Mann-Whitney U analyses were inconsistent and demonstrated less specificity for children with milder levels of social impairment. The revised algorithm demonstrated accuracy for the more severe autistic group.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1007/s10803-007-0488-8 | DOI Listing |
J Foot Ankle Res
March 2025
Department of Orthopaedic Surgery, Akershus University Hospital, Lørenskog, Norway.
Introduction: Diabetes-related foot ulcer (DFU) is the leading cause for lower extremity amputations (LEAs) in western countries, and may cause social isolation, depression, and death. However, people with DFU are not offered the same prioritized care as cancer patients, despite comparable mortality rates. We therefore decided to create a clinical pathway for patients with DFU.
View Article and Find Full Text PDFAlzheimers Res Ther
January 2025
Fraunhofer Institute for Algorithms and Scientific Computing SCAI, Sankt Augustin, Germany.
Background: Alzheimer's disease (AD) is a progressive neurodegenerative disorder affecting millions worldwide, leading to cognitive and functional decline. Early detection and intervention are crucial for enhancing the quality of life of patients and their families. Remote Monitoring Technologies (RMTs) offer a promising solution for early detection by tracking changes in behavioral and cognitive functions, such as memory, language, and problem-solving skills.
View Article and Find Full Text PDFArthroscopy
January 2025
The Everett J. and Marian Gordon Professor of Orthopaedic Surgery and Sports Medicine The Rothman Institute, Thomas Jefferson University Philadelphia, Pennsylvania, U.S.A. Electronic address:
Current surgical treatment options for ulnar collateral ligament injury of the elbow include both reconstruction and repair. A growing amount of research has evaluated the outcomes of these various techniques in a variety of study designs. Large national database assessment indicates that overall failure rates are low and complication rates are similar between UCL reconstruction and UCL repair techniques.
View Article and Find Full Text PDFRadiol Med
January 2025
Department of Radiology, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
Purpose: To develop an artificial intelligence (AI) algorithm for automated measurements of spinopelvic parameters on lateral radiographs and compare its performance to multiple experienced radiologists and surgeons.
Methods: On lateral full-spine radiographs of 295 consecutive patients, a two-staged region-based convolutional neural network (R-CNN) was trained to detect anatomical landmarks and calculate thoracic kyphosis (TK), lumbar lordosis (LL), sacral slope (SS), and sagittal vertical axis (SVA). Performance was evaluated on 65 radiographs not used for training, which were measured independently by 6 readers (3 radiologists, 3 surgeons), and the median per measurement was set as the reference standard.
Clin Exp Med
January 2025
Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
The role of metabolic reprogramming of the tumor immune microenvironment in cancer development and immune escape has increasingly attracted attention. However, the predictive value of differences in metabolism-immune microenvironment on the prognosis of colon cancer (CC) and the response to immunotherapy have not been elucidated. The aim of this study was to investigate changes in metabolism and immune profile of CC and to identify a reliable signature for predicting prognosis and therapeutic response.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!