AI Article Synopsis
- - Chronic meningitis can sometimes be linked to neurocysticercosis, a condition caused by the Taenia solium parasite, although it’s not very common.
- - In this study, researchers used a quick test called Co-agglutination (Co-A) to find Cysticercus antigens in 67 cerebrospinal fluid samples from patients with unexplained chronic meningitis, comparing it to another method called ELISA which tests for antibodies.
- - They found that 11.94% of patients had either Cysticercus antigens or antibodies, indicating a potential connection to cysticercosis, but it remains unclear if this is the cause of all chronic meningitis cases.
Article Abstract
Chronic meningitism is a less frequent manifestation of neurocysticercosis caused by Taenia solium cysticerci. In the present study we used Co-agglutination (Co-A), a simple and rapid slide agglutination test to detect specific Cysticercus antigen in the 67 cerebrospinal fluid (CSF) samples from patients with chronic meningitis of unknown etiology. The results were compared with that of ELISA for detection of antibodies. Among these samples four (5.97%) were positive for Cysticercus antigen by Co-A test and six (8.95%) were positive for antibodies by ELISA. Two samples were positive by both Co-A and ELISA, two were positive only by Co-A and four were positive only by ELISA. In the present study, although Cysticercus antigen and antibodies were present in CSF samples from eight (11.94%) patients, we cannot affirm that all the cases of chronic meningitis are due to cysticercosis, but for any case of chronic meningitis of unknown origin, it would be useful to consider the possibility of cysticercal meningitis.
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| http://dx.doi.org/10.1590/s0036-46652007000500011 | DOI Listing |
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