Sodium tetradecyl sulfate is a sclerosing agent that has been widely used to treat varicose veins of the legs and digestive tract. Despite the multitude of side-effects of sclerotherapy procedures and sclerosing-drug administration, the medical literature reports only on a few cases of life-threatening hypersensitivity reactions resulting from sodium tetradecyl sulfate therapy. A case is reported of a 49-year-old woman who developed anaphylactoid reaction after the administration of the Fibro-vein for varicose veins in the legs. Attention is drawn to this adverse event and underlines the necessity for potential hypersensitivity assessment before the drug application.
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