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The versatility of the Supinator to Posterior Interosseus Nerve (SPIN) transfer: Indications and outcomes, a Case Series.
Plast Reconstr Surg
December 2024
The Peripheral Nerve Injury Service, University Hospitals Birmingham NHS Foundation Trust, UK.
Background: Transfer of the supinator motor branches to the posterior interosseous nerve (SPIN) was first described as a reliable method of restoration of digit extension in cases of paralysis when there is retained function in the 5th and 6th cervical nerve roots with loss of function in the 8th cervical nerve root.
Methods: We performed a retrospective review of all the SPIN transfers that were performed in our unit which included 16 limbs in 14 patients over a 6-year period. The median age was 49 years (range 22-74).
Application of 3D-printed porous prosthesis for the reconstruction of infectious bone defect with concomitant severe soft tissue lesion: a case series of 13 cases.
BMC Musculoskelet Disord
December 2024
Department of Orthopedics, Peking University Third Hospital, No.49, North Garden Rd, HaiDian District, Beijing, 100191, China.
Background: Treating infectious bone defects combined with large soft-tissue lesions poses significant clinical challenges. Herein, we introduced a modified two-stage treatment approach involving the implantation of 3D-printed prostheses and flap repair to treat large segmental infectious tibial bone defects.
Method: We conducted a retrospective study of 13 patients treated at our center between April 2018 and March 2022 for tibial infections owing to posttraumatic infection and chronic osteomyelitis combined with soft tissue defects.
Wound-related Pain and Quality of Life in Patients with Chronic Wounds in a Metropolitan City in Nigeria: An Analytic Cross-sectional Study.
J West Afr Coll Surg
July 2024
Department of Plastic, Reconstructive and Aesthetic Surgery, University College Hospital, Ibadan, Nigeria.
Background: The prevalence of chronic wounds is expected to rise with the increasing elderly population in the society. This rise in prevalence of chronic wounds comes with its consequences such as wound pain and interference with activities of daily living. There's a paucity of data on the impact of chronic wounds in our clime.
View Article and Find Full Text PDFPopliteal Neurovascular Bundle Medialization and Axial Flap Rotation to Avoid Bone Impingement in Tibial Turn-up Plasty: A Case Report.
Rev Bras Ortop (Sao Paulo)
November 2024
Departmento de Cirurgia Ortopédica, IRCCS Azienda Ospedaliera Universitaria di Bologna, Bolonha, Itália.
A 33-year-old male patient developed distal femur chronic osteomyelitis with massive bone loss after an open grade-3b fracture. Following several failed treatments to eradicate infection, a tibial turn-up procedure was performed to provide a stable and functional stump. To avoid neurovascular problems, the popliteal vessels and sciatic nerve were moved medially, and the flap was rotated externally to decrease the collapse.
View Article and Find Full Text PDFTransient Receptor Potential Ankyrin 1 (TRPA1) Mediated LPS-Induced Inflammation in Periodontal Ligament Stem Cells by Inhibiting the Phosphorylation of JNK.
Stem Cells Int
December 2024
State Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Clinical Research Center for Oral Diseases, Department of Orthodontics, School of Stomatology, The Fourth Military Medical University, No. 169 Changle West Road, Xi'an 710032, China.
Transient receptor potential ankyrin 1 (TRPA1) molecule is an important type of transient receptor potential (TRP) cation channels, which can cause extracellular Ca to flow into cells after activation. TRPA1 plays an important role in acute and chronic pain, inflammation, kidney disease, cough and asthma, osteoarthritis, cardiovascular disease, obesity, diabetes, and other diseases. In this study, the expression of interleukin (IL)-1, IL-6, and IL-8 in periodontal ligament stem cells (PDLSCs) treated by lipopolysaccharide (LPS) and the effect of LPS on PDLSCS proliferation were detected.
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