Bone densitometry is an effective screening tool for osteoporosis; however, problems may exist when patients present with high variability between readings at different sites. The purpose of this study was to compare bone mineral density measures of the femur, spine and whole body using dual-energy x-ray absorptiometry. While correlations between anatomic regions were high, substantial variability existed for participants which presents the potential for misdiagnosis and confusion. Densitometry screening using both spine and femur is recommended; information regarding readings that are variable are provided. Applications for bone mineral density screening and counseling are presented for primary care physicians.

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