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Sequence specific interstrand photocrosslinking for effective SNP typing. | LitMetric
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Sequence specific interstrand photocrosslinking for effective SNP typing.

Takehiro Ami Katsuya Ito Yoshinaga Yoshimura Kenzo Fujimoto

Org Biomol Chem

School of Materials Science, Japan Advanced Institute of Science and Technology, Ishikawa 923-1292, Japan.

Published: August 2007

We describe a simple and inexpensive SNP typing method by using sequence specific interstrand photocrosslinking via p-carbamoylvinyl phenol nucleosides. Interstrand photocrosslinking showed a high degree of single nucleotide specificity as high as 10(3)-fold and more, and can be used in the diagnostic detection of DNA sequences.

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 Source
http://dx.doi.org/10.1039/b708264aDOI Listing

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