Synthesis of pyran and pyranone natural products.

Molecules

School of Chemistry, The University of Melbourne, Parkville, Victoria 3010, Australia.

Published: May 2004

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Article Abstract

An overview of the synthesis of the fungal metabolites (+)-dermolactone, (-)- semixanthomegnin, (+)- and (-)-mellein, (-)-ochratoxin alpha, (-)-(1R,3S)-thysanone, the enantiopure ventiloquinones L, E and G, and 8-desmethyleleutherin from a common chiral intermediate, is presented. Further methodology leading potentially toward extended quinones such as (3S,3'S)-xylindein is also outlined.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147286PMC
http://dx.doi.org/10.3390/90600498DOI Listing

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