A new secopyrrolizidine alkaloid, acetylanonamine, was isolated from Senecio anonymus. The structure was established by high resolution nmr (1H-1H COSY and 1H-13C HETCOR), ms, comparison of these spectral data with those of anonamine, and synthesis of 1 from 2.

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http://dx.doi.org/10.1021/np50077a035DOI Listing

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A new secopyrrolizidine alkaloid, acetylanonamine, was isolated from Senecio anonymus. The structure was established by high resolution nmr (1H-1H COSY and 1H-13C HETCOR), ms, comparison of these spectral data with those of anonamine, and synthesis of 1 from 2.

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lambda(Mo K alpha) = 0.71069 A, T = 298 K. Anonamine (I) (12,21-dihydroxy-4-methyl-4,8-secosenecionan-8,11,16-trione): C19H27NO7, Mr = 381.

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