The absolute stereo structure of the natural product laurenditerpenol (1S, 6R, 7S, 10R, 11R, 14S, 15R) has been accomplished from eight plausible stereoisomers by its first asymmetric total synthesis in a highly convergent and flexible synthetic pathway. Six stereoisomers of laurenditerpenol were synthesized and evaluated for their biological activity.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911032PMC
http://dx.doi.org/10.1021/jm7011062DOI Listing

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