The first direct C-H arylation of purine nucleosides.

Chem Commun (Camb)

Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Gilead & IOCB Research Center, Flemingovo nam. 2, CZ-16610 Prague 6, Czech Republic.

Published: December 2007

Pd-catalyzed direct C-H arylation of unprotected purine nucleosides with aryl iodides at position 8 was developed to allow a straightforward single-step introduction of diverse aryl groups.

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Source
http://dx.doi.org/10.1039/b714253fDOI Listing

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