We describe a scrub typhus patient with acute renal failure for whom a diagnosis was made based on serology as well as immunohistochemical (IHC) staining and an electron microscopic examination (EM) of a renal biopsy specimen. For our case, we demonstrated by IHC staining and EM that renal failure was caused by acute tubular necrosis due to a direct invasion of Orientia tsutsugamushi.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292935PMC
http://dx.doi.org/10.1128/JCM.01040-07DOI Listing

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