AI Article Synopsis
- Osteoporosis is a bone disease that needs early detection, and biomarkers play a crucial role in identifying it through clinical proteomics.
- Various testing techniques, including BMD testing and optical/electrochemical methods, have been compared for effectiveness.
- Recent findings show new peaks in UV-visible spectroscopy and high sensitivity in electrochemical techniques, making them ideal for creating a new bioMEMS chip for bone marker detection.
Article Abstract
Osteoporosis is a bone disease which requires early detection. The biomarkers provide a promising challenge of clinical proteomics for early disease detection. Different techniques like BMD testing, optical and electrochemical testing have been studied comparatively. New peaks have been identified in UV-visible spectroscopy at 420nm and high sensitivity is achieved by electrochemical technique with ng/ml to pico/ml level detection of bonemarkers. An electrochemical technique is found to be the best suitable for developing a new bioMEMS chip.
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| http://dx.doi.org/10.1109/IEMBS.2007.4352776 | DOI Listing |
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