The purpose of this study was to develop a measuring system of contact force in finger-tapping of Parkinson's disease patients and to show its effectiveness for quantitative diagnosis. This system was composed of a pair of 3-axis accelerometers, a touch sensor an analog to digital converter and a personal computer (PC). Firstly, a transfer function representing relation between the contact force and the accelerometer output during the finger contact phase of finger-tapping was determined. This means that the finger-tapping contact force could be estimated from the measured acceleration by using the determined transfer function. Secondly the developed system was applied to 27 normal subjects and 16 Parkinson's diseases subjects. Score of UPDRS finger tap test was evaluated for each subject by a neurologist. Finally, these sensors were attached to subject's index finger and thumb, and sensor signals were recorded and processed within the PC. The subjects were asked to execute continuous finger taps movement for 60 s. It was shown that the contact force was smaller as the subject was with the larger UPDRS score of tap test.
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http://dx.doi.org/10.1109/IEMBS.2007.4352549 | DOI Listing |
J Biomed Mater Res B Appl Biomater
January 2025
Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai, P. R. China.
Massive bleeding and bacterial infection of wounds may be life-threatening or even lead to death. Nowadays, gelatin-based hemostatic sponges have been widely used, but gelatin is not antibacterial and has poor structural stability. In this study, we mixed an antibacterial polypeptide, ε-poly-L-lysine (EPL), into gelatin.
View Article and Find Full Text PDFBioact Mater
April 2025
Laboratory of Experimental Neuroregeneration, Spinal Cord Injury Center, Heidelberg University Hospital, 69118, Heidelberg, Germany.
Biomaterial scaffold engineering presents great potential in promoting axonal regrowth after spinal cord injury (SCI), yet persistent challenges remain, including the surrounding host foreign body reaction and improper host-implant integration. Recent advances in mechanobiology spark interest in optimizing the mechanical properties of biomaterial scaffolds to alleviate the foreign body reaction and facilitate seamless integration. The impact of scaffold stiffness on injured spinal cords has not been thoroughly investigated.
View Article and Find Full Text PDFHeliyon
December 2024
Ingeniería Electroquímica y Corrosión, Instituto Unversitario de Seguridad Industrial, Radiofísica y Medioambiental, Universitat Politècnica de València, C/Camino de Vera s/n, 46022, Valencia, Spain.
In this research work, four distinct WO electrodes were synthesized and coated with three different polymers, known as polypyrrole (PPy), poly(3,4-ethylenedioxythiophene) in poly(4-styrenesulfonate) (PEDOT:PSS) and polyaniline (PANi), using electropolymerization techniques. The morphological features of the samples were thoroughly characterized through Field Emission Scanning Electron Microscopy (FE-SEM) and Atomic Force Microscopy (AFM) analyses. Additionally, contact angle measurements and electrochemical characterizations were used to verify the performance of each electrode, aiding in the prediction of their suitability for energy storage applications in lithium-ion batteries.
View Article and Find Full Text PDFBackground And Purpose: Anterior cruciate ligament (ACL) tears often occur due to non-contact mechanisms in landing within females. Impact loading and aberrant landings may be addressed with augmented feedback training. The purpose of this study was to identify which female athletes most readily respond to a single session of augmented feedback to attenuate vGRF, by considering baseline peak vGFR and change in vGRF during training.
View Article and Find Full Text PDFACS Omega
December 2024
State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration & National Clinical Research Center for Oral Diseases & Shaanxi Engineering Research Center for Dental Materials and Advanced Manufacture, Department of Oral Implants, School of Stomatology, The Fourth Military Medical University, Xi'an 710032, Shaanxi, P. R. China.
Metal 3D printing has been used in the manufacturing of dental implants. Its technical advantages include high material utilization and the capacity to form arbitrarily complex structures. However, 3D printing alone is insufficient for manufacturing two-stage titanium implants due to the limited precision in printing titanium alloy parts.
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