This paper presents a model-based method for the analysis of regional myocardial strain, based on echocardiography and Tissue Doppler Imaging (TDI). A multi-formalism, tissue-level electromechanical model of the left ventricle is proposed. The parameters of the model are identified in order to reproduce regional strain signal morphologies obtained from a healthy subject and a patient presenting a dilated cardiomyopathy. The parameters identified for the DCM patient allow the localization of the failing myocardial segments and may be useful for a better design of cardiac resynchronization therapy on heart failure patients.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099576 | PMC |
| http://dx.doi.org/10.1109/IEMBS.2007.4352505 | DOI Listing |
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