Placental p,p'-dichlorodiphenyldichloroethylene and cord blood immune markers.

Pediatr Allergy Immunol

Department of Epidemiology and Biostatistics, Norman J. Arnold School of Public Health, University of South Carolina, Columbia, SC 29208-0001, USA.

Published: November 2007

Placental p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE) concentration and cord blood atopic markers were determined in 19 neonates. Increased placental p,p'-DDE was associated with a statistically significant increase in cord plasma interleukin (IL)-13. Furthermore, both cord plasma IL-4/interferon (IFN)-gamma and IL-13/IFN-gamma ratios were significantly positively associated with placental p,p'-DDE concentration.

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http://dx.doi.org/10.1111/j.1399-3038.2007.00546.xDOI Listing

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