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Perianal Pseudoverrucous Papules and Nodules in an Elderly Patient.

Clin Cosmet Investig Dermatol

October 2023

Department of Dermatology, College of Medicine, Chungbuk National University, Cheongju, Chungbuk, South Korea.

Pseudoverrucous papules and nodules is a reaction to irritation usually associated with urostomies. We report a case of perianal pseudoverrucous papules and nodules in an elderly patient who developed a characteristic diaper dermatitis after infrequent diaper change. The perianal papulonodular lesions improved after saline wet dressing and topical steroid application.

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Article Synopsis
  • - Nevoid hyperkeratosis of the nipple and areola (NHKNA) is a rare skin condition, especially in its type II form, which can develop from irritant skin conditions like erosive papulonodular dermatitis that occurs in areas prone to friction and moisture.
  • - The case discussed involves a patient who had previously suffered from erosive papulonodular dermatitis after undergoing an ileostomy, later showing classic signs of NHKNA, which were confirmed through clinical and histological analysis.
  • - Treatment for type II NHKNA usually involves addressing the underlying skin issue; in this instance, reversing the ileostomy and implementing barrier protection successfully resolved the patient's NHKNA lesions.
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Background: Multicentric reticulohistiocytosis (MRH) is a rare non-Langerhans histiocytosis of unknown etiology characterized by papulonodular skin lesions and progressive, erosive arthritis. To date, there have been approximately 300 cases of MRH reported worldwide. The majority of patients are Caucasian from western countries, and Asian patients are rare.

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Clinical characteristics of multicentric reticulohistiocytosis and distinguished features from rheumatoid arthritis: a single-center experience in China.

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Department of Rheumatology and Clinical Immunology, Peking Union Medical College, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, National Clinical Research Center for Dermatologic and Immunologic Diseases, Ministry of Science& Technology, State Key Laboratory of Complex Severe and Rare Diseases, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Beijing, 100730, China.

Objective: To investigate the clinical features of multicentric reticulohistiocytosis (MRH).

Methods: The clinical manifestations, laboratory examination results and histologic characteristics of eleven patients with MRH were collected and compared with those of 33 patients with rheumatoid arthritis.

Results: In total, 72.

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